Paneth cell: Difference between revisions

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[[Image: Paneth cell metaplasia in the left colon -- extremely high mag.jpg | thumb | right |Paneth cell metaplasia. [[H&E stain]].]]
[[Image: Paneth cell metaplasia in the left colon -- extremely high mag.jpg | thumb | right |Paneth cell metaplasia and lamina propria [[eosinophil]]s. [[H&E stain]]. ]]
The '''Paneth cell''' is characteristic of the [[small intestine]]. It is also normal in the [[cecum]], ascending colon and transverse colon.
The '''Paneth cell''' is characteristic of the [[small intestine]]. It is also normal in the [[cecum]], ascending colon and transverse colon.


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If PCM is present:
If PCM is present:
*Think of [[inflammatory bowel disease]] and other long-standing injurious processes.
*Think of [[inflammatory bowel disease]] and other long-standing injurious processes.
*PCM in the context of colorectal adenomas may be associated with a higher risk of colorectal neoplasia.<ref name=pmid23232853>{{Cite journal  | last1 = Pai | first1 = RK. | last2 = Rybicki | first2 = LA. | last3 = Goldblum | first3 = JR. | last4 = Shen | first4 = B. | last5 = Xiao | first5 = SY. | last6 = Liu | first6 = X. | title = Paneth cells in colonic adenomas: association with male sex and adenoma burden. | journal = Am J Surg Pathol | volume = 37 | issue = 1 | pages = 98-103 | month = Jan | year = 2013 | doi = 10.1097/PAS.0b013e318267b02e | PMID = 23232853 }}</ref>


==Microscopic==
==Microscopic==
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*[[Inflammatory bowel disease]].
*[[Inflammatory bowel disease]].
*[[Colon]].
*[[Colon]].
*[[Paneth cell-like change of the prostate gland]].


==References==
==References==