Difference between revisions of "Esophageal stricture"
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==General== | ==General== | ||
Strictures in general: | Strictures in general: | ||
*Malignant - it is the | *Malignant - it is the pathologist's job to help rule-out these. | ||
*Benign. | *Benign. | ||
*Most are distal.<ref name=pmid6512226>{{Cite journal | last1 = Kozarek | first1 = RA. | title = Proximal strictures of the esophagus. | journal = J Clin Gastroenterol | volume = 6 | issue = 6 | pages = 505-11 | month = Dec | year = 1984 | doi = | PMID = 6512226 }}</ref> | |||
Treatment: | Treatment: | ||
| Line 15: | Line 16: | ||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Squamous mucosa: | *Squamous mucosa with irritation: | ||
**+/-Keratinization. | **+/-Keratinization. | ||
**Intraepithelial lymphocytes. | **Intraepithelial lymphocytes. | ||
**Basal cell hyperplasia. | **Basal cell hyperplasia. | ||
*Fibrosis (deep) - usually not seen. | |||
DDx: | DDx: | ||
Latest revision as of 02:59, 22 February 2014
Esophageal stricture is usually a clinical diagnosis. Considered broadly, strictures may be benign or malignant.
This article deals primarily with benign stricture of the esophagus or benign esophageal stricture.
General
Strictures in general:
- Malignant - it is the pathologist's job to help rule-out these.
- Benign.
- Most are distal.[1]
Treatment:
Microscopic
Features:
- Squamous mucosa with irritation:
- +/-Keratinization.
- Intraepithelial lymphocytes.
- Basal cell hyperplasia.
- Fibrosis (deep) - usually not seen.
DDx:
- GERD.
- Barrett's esophagus.
- Squamous cell carcinoma of the esophagus.
- Adenocarcinoma of the esophagus.
Sign out
ESOPHAGUS, BIOPSY: - SQUAMOUS MUCOSA WITH BASAL CELL HYPERPLASIA, MILD INTRAEPITHELIAL EDEMA, FOCAL EARLY KERATINIZATION AND INTRAEPITHELIAL LYMPHOCYTES. - SCANT COLUMNAR EPITHELIUM WITH MODERATE CHRONIC INACTIVE INFLAMMATION. - NEGATIVE FOR INTESTINAL METAPLASIA. - NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.
See also
References
- ↑ Kozarek, RA. (Dec 1984). "Proximal strictures of the esophagus.". J Clin Gastroenterol 6 (6): 505-11. PMID 6512226.
- ↑ Hourneaux de Moura, EG.; Toma, K.; Goh, KL.; Romero, R.; Dua, KS.; Felix, VN.; Levine, MS.; Kochhar, R. et al. (Oct 2013). "Stents for benign and malignant esophageal strictures.". Ann N Y Acad Sci 1300: 119-43. doi:10.1111/nyas.12242. PMID 24117639.
- ↑ Singhal, S.; Hasan, SS.; Cohen, DC.; Pfanner, T.; Reznik, S.; Duddempudi, S. (Sep 2013). "Multi-disciplinary approach for management of refractory benign occlusive esophageal strictures.". Therap Adv Gastroenterol 6 (5): 365-70. doi:10.1177/1756283X13492000. PMID 24003337.