Difference between revisions of "Sudden natural death"
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==By system== | ==By system== | ||
===Respiratory<ref name=pmid16410164>{{cite journal |author=de la Grandmaison GL |title=Is there progress in the autopsy diagnosis of sudden unexpected death in adults? |journal=Forensic Sci. Int. |volume=156 |issue=2-3 |pages=138–44 |year=2006 |month=January |pmid=16410164 |doi=10.1016/j.forsciint.2004.12.024 |url=}}</ref>=== | ===Respiratory<ref name=pmid16410164>{{cite journal |author=de la Grandmaison GL |title=Is there progress in the autopsy diagnosis of sudden unexpected death in adults? |journal=Forensic Sci. Int. |volume=156 |issue=2-3 |pages=138–44 |year=2006 |month=January |pmid=16410164 |doi=10.1016/j.forsciint.2004.12.024 |url=}}</ref>=== | ||
*Anaphylaxis. | *[[Anaphylaxis]]. | ||
*[[Asthma]]. | *[[Asthma]]. | ||
*[[Pulmonary embolism]]. | *[[Pulmonary embolism]]. | ||
===Cerebral=== | ===Cerebral=== | ||
*SUDEP (sudden unexpected death in epilepsy). | *[[SUDEP]] (sudden unexpected death in [[epilepsy]]). | ||
=== | ===Sudden cardiac death=== | ||
====Older==== | ====Older==== | ||
*Atherosclerotic heart disease (ASHD); [[AKA]] coronary artery disease (CAD). | *[[Atherosclerotic heart disease]] (ASHD); [[AKA]] coronary artery disease (CAD). | ||
*[[ | *[[Hypertensive heart disease]] - a heart > ~400 g is considered good enough if nothing else is present.<ref>MSP. 29 September 2010.</ref> | ||
====Younger==== | ====Younger==== | ||
* | *[[Arrhythmogenic right ventricular cardiomyopathy]]. | ||
* | *[[Hypertrophic cardiomyopathy]], e.g. [[hypertrophic obstructive cardiomyopathy]] (HOCM). | ||
Notes: | Notes: | ||
*The mechanism is usually arrhythmia | *The mechanism is usually [[cardiac arrhythmia|arrhythmia]]. | ||
**Generally, this is usually not provable at [[autopsy]]; however, some findings have been proposed.<ref name=pmid15837088>{{Cite journal | last1 = Baroldi | first1 = G. | last2 = Silver | first2 = MD. | last3 = Parolini | first3 = M. | last4 = Pomara | first4 = C. | last5 = Turillazzi | first5 = E. | last6 = Fineschi | first6 = V. | title = Myofiberbreak-up: a marker of ventricular fibrillation in sudden cardiac death. | journal = Int J Cardiol | volume = 100 | issue = 3 | pages = 435-41 | month = Apr | year = 2005 | doi = 10.1016/j.ijcard.2004.10.007 | PMID = 15837088 }}</ref> | |||
====Detailed cardiac<ref name=pmid16410164/>==== | ====Detailed cardiac<ref name=pmid16410164/>==== | ||
*ASHD | *[[ASHD]]. | ||
*Cardiomyopathy. | *[[Cardiomyopathy]]. | ||
**Hypertrophic | **[[Hypertrophic cardiomyopathy]]. | ||
**[[Arrhythmogenic right ventricular cardiomyopathy]] ( | **[[Arrhythmogenic right ventricular cardiomyopathy]] (ARVC). | ||
** | **[[Dilated cardiomyopathy]] (DCM). | ||
*Lymphocytic myocarditis. | *[[Lymphocytic myocarditis]]. | ||
*Floppy mitral valve | *[[Floppy mitral valve]]. | ||
*Aortic valve stenosis. | *[[Aortic valve stenosis]]. | ||
*Congenital cardiac abnormality. | *Congenital cardiac abnormality. | ||
*Coronary artery dissection. | *Coronary artery dissection. | ||
*Aortic dissection. | *[[Aortic dissection]]. | ||
*Arrhythmia.<ref>URL: [http://www.sads.org.uk/causes_of_sads.htm http://www.sads.org.uk/causes_of_sads.htm]. Accessed on: 29 September 2010.</ref> | *[[Cardic arrhythmia|Arrhythmia]].<ref>URL: [http://www.sads.org.uk/causes_of_sads.htm http://www.sads.org.uk/causes_of_sads.htm]. Accessed on: 29 September 2010.</ref> | ||
**Long QT syndrome. | **Long QT syndrome. | ||
**Brugada syndrome. | **Brugada syndrome. | ||
| Line 44: | Line 45: | ||
**Sodium channel disease. | **Sodium channel disease. | ||
**Idiopathic ventricular fibrillation. | **Idiopathic ventricular fibrillation. | ||
*Tumours. | |||
**[[Cystic tumour of the atrioventricular nodal region]]. | |||
Post-mortem (molecular) testing for arrhythmias:<ref>MSP. 29 September 2010:</ref> | Post-mortem (molecular) testing for arrhythmias:<ref>MSP. 29 September 2010:</ref> | ||
| Line 54: | Line 57: | ||
*Ruptured AAA. | *Ruptured AAA. | ||
*Peptic ulcer. | *Peptic ulcer. | ||
*Cerebral aneurysm. | *[[Cerebral aneurysm]]. | ||
==See also== | ==See also== | ||
*[[Forensic pathology]]. | *[[Forensic pathology]]. | ||
*[[Channelopathies]]. | |||
==Reference== | ==Reference== | ||
Latest revision as of 05:18, 21 July 2016
Sudden natural death happens. It must be differentiated from other ways of dying (suicide, homicide, accidental).
By system
Respiratory[1]
Cerebral
Sudden cardiac death
Older
- Atherosclerotic heart disease (ASHD); AKA coronary artery disease (CAD).
- Hypertensive heart disease - a heart > ~400 g is considered good enough if nothing else is present.[2]
Younger
- Arrhythmogenic right ventricular cardiomyopathy.
- Hypertrophic cardiomyopathy, e.g. hypertrophic obstructive cardiomyopathy (HOCM).
Notes:
- The mechanism is usually arrhythmia.
Detailed cardiac[1]
- ASHD.
- Cardiomyopathy.
- Lymphocytic myocarditis.
- Floppy mitral valve.
- Aortic valve stenosis.
- Congenital cardiac abnormality.
- Coronary artery dissection.
- Aortic dissection.
- Arrhythmia.[4]
- Long QT syndrome.
- Brugada syndrome.
- Short QT syndrome.
- Catecholaminergic polymorphic ventricular tachycardia (CPVT).
- Anomalous conduction pathways.
- Dysplasia of nodal arteries.
- Atrioventricular node tumour.
- Sodium channel disease.
- Idiopathic ventricular fibrillation.
- Tumours.
Post-mortem (molecular) testing for arrhythmias:[5]
- CPVT.
- Sodium channel disease.
- Brugada syndrome.
By mechanism
Hemorrhagic[1]
- Ruptured AAA.
- Peptic ulcer.
- Cerebral aneurysm.
See also
Reference
- ↑ 1.0 1.1 1.2 de la Grandmaison GL (January 2006). "Is there progress in the autopsy diagnosis of sudden unexpected death in adults?". Forensic Sci. Int. 156 (2-3): 138–44. doi:10.1016/j.forsciint.2004.12.024. PMID 16410164.
- ↑ MSP. 29 September 2010.
- ↑ Baroldi, G.; Silver, MD.; Parolini, M.; Pomara, C.; Turillazzi, E.; Fineschi, V. (Apr 2005). "Myofiberbreak-up: a marker of ventricular fibrillation in sudden cardiac death.". Int J Cardiol 100 (3): 435-41. doi:10.1016/j.ijcard.2004.10.007. PMID 15837088.
- ↑ URL: http://www.sads.org.uk/causes_of_sads.htm. Accessed on: 29 September 2010.
- ↑ MSP. 29 September 2010: