Difference between revisions of "Acute esophagitis"
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'''Acute esophagitis''' occasionally afflicits the [[esophagus]]. | '''Acute esophagitis''' occasionally afflicits the [[esophagus]]. | ||
==General== | |||
*Benign. | *Benign. | ||
*Usually older men.<ref name=pmid23831655>{{Cite journal | last1 = Kawauchi | first1 = H. | last2 = Ohta | first2 = T. | last3 = Matsubara | first3 = Y. | last4 = Yoshizaki | first4 = K. | last5 = Sakamoto | first5 = J. | last6 = Amitsuka | first6 = H. | last7 = Kimura | first7 = K. | last8 = Maemoto | first8 = A. | last9 = Orii | first9 = F. | title = Clinicopathological study of acute esophageal mucosal lesion. | journal = Nihon Shokakibyo Gakkai Zasshi | volume = 110 | issue = 7 | pages = 1249-57 | month = Jul | year = 2013 | doi = | PMID = 23831655 }}</ref> | *Usually older men.<ref name=pmid23831655>{{Cite journal | last1 = Kawauchi | first1 = H. | last2 = Ohta | first2 = T. | last3 = Matsubara | first3 = Y. | last4 = Yoshizaki | first4 = K. | last5 = Sakamoto | first5 = J. | last6 = Amitsuka | first6 = H. | last7 = Kimura | first7 = K. | last8 = Maemoto | first8 = A. | last9 = Orii | first9 = F. | title = Clinicopathological study of acute esophageal mucosal lesion. | journal = Nihon Shokakibyo Gakkai Zasshi | volume = 110 | issue = 7 | pages = 1249-57 | month = Jul | year = 2013 | doi = | PMID = 23831655 }}</ref> | ||
*Classically present with bleeding.<ref name=pmid23831655/> | *Classically present with bleeding.<ref name=pmid23831655/> | ||
==Microscopic== | |||
Features: | Features: | ||
*Intraepithelial [[neutrophil]]s - '''key feature'''. | *Intraepithelial [[neutrophil]]s - '''key feature'''. | ||
*Basal cell hyperplasia. | *Basal cell hyperplasia. | ||
*No infectious agent identified - '''important'''. | *No infectious agent identified - '''important'''. | ||
Note: | |||
*One should: | |||
**Do stains to exclude fungal organisms. | |||
**Check the history for immune deficiency - if this isn't on the provided history. | |||
DDx: | DDx: | ||
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*[[Herpes esophagitis]]. | *[[Herpes esophagitis]]. | ||
==Stains== | |||
*[[PAS-D stain]] -ve for fungal organisms. | *[[PAS-D stain]] -ve for fungal organisms. | ||
*[[GMS stain]] -ve for fungal organisms. | *[[GMS stain]] -ve for fungal organisms. | ||
===Sign out | ==IHC== | ||
*CMV -ve. | |||
*HSV1 -ve. | |||
*HSV2 -ve. | |||
==Sign out== | |||
<pre> | <pre> | ||
ESOPHAGUS, BIOPSY: | ESOPHAGUS, BIOPSY: | ||
Latest revision as of 13:07, 23 October 2015
| Acute esophagitis | |
|---|---|
| External resources | |
| EHVSC | 10168 |
Acute esophagitis occasionally afflicits the esophagus.
General
Microscopic
Features:
- Intraepithelial neutrophils - key feature.
- Basal cell hyperplasia.
- No infectious agent identified - important.
Note:
- One should:
- Do stains to exclude fungal organisms.
- Check the history for immune deficiency - if this isn't on the provided history.
DDx:
Stains
- PAS-D stain -ve for fungal organisms.
- GMS stain -ve for fungal organisms.
IHC
- CMV -ve.
- HSV1 -ve.
- HSV2 -ve.
Sign out
ESOPHAGUS, BIOPSY: - ACUTE ESOPHAGITIS. -- NO FUNGAL ORGANISMS IDENTIFIED WITH PAS-D AND GMS STAINING. - NO COLUMNAR EPITHELIUM IDENTIFIED. - NEGATIVE FOR DYSPLASIA.