Foreskin: Difference between revisions

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#redirect [[Ditzels#Foreskin]]
The [[foreskin]] is a common [[ditzel]].
 
==General==
Indications:
*[[Phimosis]].
 
Main considerations:
*[[Squamous cell carcinoma]].
*[[Lichen sclerosus]], [[AKA]] ''balanitis xerotica obliterans''.
*[[Lichen planus]].
*Infection, e.g. [[syphilis]], [[candidiasis]].
*[[Zoon balanitis]] - abundant [[plasma cell]]s.
 
Note:
*Malignant and premalignant lesions are uncommon: 21 of 414 cases.<ref>{{cite journal | authors = West DS, Papalas JA, Selim MA, Vollmer RT | title = Dermatopathology of the foreskin: an institutional experience of over 400 cases | journal = J Cutan Pathol | volume = 40 | issue = 1 | pages = 11–8 | date = January 2013 | pmid = 23106553 | doi = 10.1111/cup.12032}}</ref>
 
==Microscopic==
Features:
*Usu. fibrotic dermis.
*+/-Inflammation.
 
DDx:
*See ''[[Penis]].
 
===Sign out===
<pre>
Foreskin, Circumcision:
- Benign squamous mucosa within normal limits, consistent with foreskin.
</pre>
 
<pre>
A. Foreskin, Circumcision:
- Benign squamous mucosa without significant histopathology, consistent with foreskin.
</pre>
 
<pre>
Foreskin, Circumcision:
- Benign squamous mucosa with mild patchy chronic inflammation at the epidermal-dermal interface.
- NEGATIVE for dysplasia and NEGATIVE for malignancy.
</pre>
 
<pre>
Foreskin, Circumcision:
- Squamous mucosa with mild-to-moderate acute and chronic
  (lymphocytic) lichenoid inflammation.
- NEGATIVE for evidence of lichen sclerosus.
- NEGATIVE for dysplasia and NEGATIVE for malignancy.
 
Comment:
A PASD stain is NEGATIVE for micro-organisms.
</pre>
 
====Micro====
The section shows squamous mucosa with mild basal pigmentation and subepithelial fibrous tissue. The epithelium matures to the surface. Significant inflammation is ABSENT. Atypia is ABSENT.
 
===Spongiotic dermatitis===
<pre>
A. Foreskin, Circumcision:
- Skin with chronic mixed interface inflammation (lymphocyte predominant) and spongiosis.
- NEGATIVE for malignancy.
</pre>
 
==See also==
[[Ditzels]].
 
==References==
{{Reflist|1}}
 
[[Category:Genitourinary pathology]]