Down syndrome: Difference between revisions
Jump to navigation
Jump to search
+genetics |
|||
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
'''Down syndrome''', is a common genetic abnormality. It may also be called '''Trisomy 21'''; however, technically this may not be completely correct in all cases. | '''Down syndrome''', abbreviated '''DS''', is a common genetic abnormality. It may also be called '''Trisomy 21'''; however, technically this may not be completely correct in all cases. | ||
==Genetics== | ==Genetics== | ||
| Line 41: | Line 41: | ||
Notes: | Notes: | ||
*Brushfield spots = white/grey spots in the iris (the "colour part" of the eye). | *Brushfield spots = white/grey spots in the iris (the "colour part" of the eye). | ||
<gallery> | |||
Image:Brushfield_eyes_magnified.jpg | Brushfield spots. (WC) | |||
</gallery> | |||
===Simplified=== | |||
Simplified version of mnemonic ''CHILD HAS PROBLEM'': | |||
#[[congenital heart disease|'''C'''ongenital heart disease]]. | |||
#'''H'''ypothyroidism. | |||
#'''I'''ncurved 5th digit (clinodactyly) / Increased gap between 1st and 2nd toe. | |||
#[[Leukemia|'''L'''eukemia]] risk x2. | |||
#'''D'''uodenal atresia. | |||
#[[Hirschsprung disease|'''H'''irschsprung disease]]. | |||
#[[Alzheimer disease|'''A'''lzheimer disease]] / Alantoaxial instability. | |||
#'''S'''hort neck. | |||
#'''P'''almar crease / Protruding [[tongue]]. | |||
#'''R'''ound face. | |||
#'''O'''cciput flat / Oblique eye fissure. | |||
#'''B'''rushfield spots / Brachycephaly. | |||
#'''L'''ow nasal bridge. | |||
#'''E'''picanthic fold / Ears folded. | |||
#'''M'''ental retardation. | |||
==See also== | ==See also== | ||