Papillary adenoma of the kidney: Difference between revisions

Jump to navigation Jump to search
Michael (talk | contribs)
49,346 edits
redirect
 
Michael (talk | contribs)
49,346 edits
 
(14 intermediate revisions by the same user not shown)
Line 1: Line 1:
#redirect [[Kidney_tumours#Papillary_adenoma_of_the_kidney]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Renal papillary adenoma -- very low mag.jpg
| Width      =
| Caption    = Papillary adenoma. [[H&E stain]].
| Synonyms  = papillary adenoma, renal papillary adenoma
| Micro      = papillae typically with foam cells, +/-psammoma bodies, low [[ISUP nucleolar grade]], ''must'' be <=1.5 cm
| Subtypes  =
| LMDDx      = [[papillary renal cell carcinoma]], [[metanephric adenoma]]
| Stains    =
| IHC        = AMACR +ve
| EM        =
| Molecular  =
| IF        =
| Gross      = typically subcapsular location
| Grossing  =
| Site      = [[kidney]] - see ''[[kidney tumours]]''
| Assdx      = often seen with [[papillary renal cell carcinoma]]
| Syndromes  =
| Clinicalhx = often an incidental finding
| Signs      =
| Symptoms  =
| Prevalence = common
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = other [[renal tumours]]
| Tx        = observation
}}
'''Papillary adenoma of the kidney''', also '''renal papillary adenoma''', is a benign [[kidney tumours|kidney tumour]] related to [[papillary renal cell carcinoma]].


==General==
*Benign.
*Considered a precursor for ''[[papillary renal cell carcinoma]]'' (PaRCC).<ref name=pmid17056094>{{Cite journal  | last1 = Wang | first1 = KL. | last2 = Weinrach | first2 = DM. | last3 = Luan | first3 = C. | last4 = Han | first4 = M. | last5 = Lin | first5 = F. | last6 = Teh | first6 = BT. | last7 = Yang | first7 = XJ. | title = Renal papillary adenoma--a putative precursor of papillary renal cell carcinoma. | journal = Hum Pathol | volume = 38 | issue = 2 | pages = 239-46 | month = Feb | year = 2007 | doi = 10.1016/j.humpath.2006.07.016 | PMID = 17056094 }}</ref>
**Stains like PaRCC.
**Found with an increased frequency within the content of PaRCC.
Note:
*In the kidney, the concept of ''[[adenoma]]'' only exists for papillary lesions that are [[papillary RCC]]-like. Small lesions that are [[chromophobe RCC]]-like or [[clear cell RCC]]-like are carcinomas.<ref name=pmid18846240/>
==Gross==
*Cortical kidney lesion.
**Usually subcapsular.
==Microscopic==
Features:
#Histomorphology of ''[[papillary renal cell carcinoma]]'' with low [[ISUP nucleolar grade]] (grade 1 or 2).
#''Must'' be <=1.5 cm as per 2016 WHO classification.<ref name=pmid26935559>{{Cite journal  | last1 = Moch | first1 = H. | last2 = Cubilla | first2 = AL. | last3 = Humphrey | first3 = PA. | last4 = Reuter | first4 = VE. | last5 = Ulbright | first5 = TM. | title = The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours. | journal = Eur Urol | volume =  | issue =  | pages =  | month = Feb | year = 2016 | doi = 10.1016/j.eururo.2016.02.029 | PMID = 26935559 }}</ref>
#*[[Diagnostic size cutoff]] - larger lesions are ''papillary renal cell carcinoma''.
Note:
*The size cut-off used to be <=0.5 cm.<ref name=pmid26935559/><ref name=Ref_GUP288>{{Ref GUP|288}}</ref><ref name=pmid18846240>{{Cite journal  | last1 = Algaba | first1 = F. | title = Renal adenomas: pathological differential diagnosis with malignant tumors. | journal = Adv Urol | volume =  | issue =  | pages = 974848 | month =  | year = 2008 | doi = 10.1155/2008/974848 | PMID = 18846240 | PMC = 2563151 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563151/?tool=pubmed }}</ref>
DDx:
*[[Papillary renal cell carcinoma]].
*[[Metanephric adenoma]].
===Images===
<gallery>
Image: Renal papillary adenoma -- very low mag.jpg | PA - very low mag.
Image: Renal papillary adenoma -- low mag.jpg | PA - low mag.
Image: Renal papillary adenoma -- intermed mag.jpg | PA - intermed. mag.
Image: Renal papillary adenoma - alt -- intermed mag.jpg | PA - intermed. mag.
Image: Renal papillary adenoma -- high mag.jpg | PA - high mag.
</gallery>
www:
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563151/figure/fig2/ Renal papillary adenoma (nih.gov)].<ref name=pmid18846240/>
==IHC==
*CK7 +ve.
*AMACR +ve.<ref name=pmid17056094/>
==See also==
*[[Kidney tumours]].
==References==
{{Reflist|2}}
[[Category:Kidney tumours]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]
Retrieved from "https://librepathology.org/wiki/Papillary_adenoma_of_the_kidney"