Difference between revisions of "Ferruginous body"

From Libre Pathology
Jump to navigation Jump to search
(redirect)
 
(→‎Stains: tweak)
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
#redirect [[Lung_tumours#Malignant_mesothelioma]]
[[Image:Ferruginous bodies - BAL - r3 -- very high mag.jpg|right|thumb|300px|Ferruginous body in a BAL. (WC)]]
'''Ferruginous body''' is a histopathologic finding in [[lung pathology]] that strongly suggests exposure to asbestos.
 
==General==
*Uncommon finding.
*Strongly suggestive of asbestos exposure.
 
Conditions associated with asbestos exposure (mnemonic ''PALM''):<ref name=Ref_PCPBoD8_375>{{Ref PCPBoD8|375}}</ref>
*[[Pleural plaques]].
*[[Asbestosis]].
*[[Lung carcinoma]].
*[[Malignant mesothelioma]].
 
==Microscopic==
Features:
*Segmented twirling baton-like structure (approximately 3-5 micrometres x 20-80 micrometres) with long slender fibre within.
*Black/brown crystal-like appearance.
 
DDx:
*Dirt - especially on H&E.
 
===Images===
<gallery>
Image:Ferruginous_body.jpg | Ferruginous bodies. (WC)
</gallery>
====Cytology====
<gallery>
Image: Ferruginous bodies - BAL - r1 -- high mag.jpg | FB - high mag. (WC)
Image: Ferruginous bodies - BAL - r1 -- very high mag.jpg | FB - very high mag. (WC)
 
Image: Ferruginous bodies - BAL - r2 -- very high mag.jpg | FB - very high mag. (WC)
 
Image: Ferruginous bodies - BAL - r3 -- high mag.jpg | FB - high mag. (WC)
Image: Ferruginous bodies - BAL - r3 -- very high mag.jpg | FB - very high mag. (WC)
Image:Carcinoma asbestos body lung.jpg | Ferruginous body in carcinoma - cytology. (WC/Alex Brollo)
</gallery>
 
==Stains==
*[[Prussian blue stain]] +ve.
 
==Sign out==
<pre>
Comment:
No cell block is available for further work-up, e.g. iron staining.
 
The findings herein should be correlated with imaging and the clinical history.
Ferruginous bodies are associated asbestos exposure.
</pre>
 
==See also==
*[[Malignant mesothelioma]].
 
==References==
{{Reflist|1}}
 
[[Category:Pulmonary pathology]]

Latest revision as of 17:46, 20 May 2018

Ferruginous body in a BAL. (WC)

Ferruginous body is a histopathologic finding in lung pathology that strongly suggests exposure to asbestos.

General

  • Uncommon finding.
  • Strongly suggestive of asbestos exposure.

Conditions associated with asbestos exposure (mnemonic PALM):[1]

Microscopic

Features:

  • Segmented twirling baton-like structure (approximately 3-5 micrometres x 20-80 micrometres) with long slender fibre within.
  • Black/brown crystal-like appearance.

DDx:

  • Dirt - especially on H&E.

Images

Cytology

Stains

Sign out

Comment:
No cell block is available for further work-up, e.g. iron staining.

The findings herein should be correlated with imaging and the clinical history. 
Ferruginous bodies are associated asbestos exposure.

See also

References

  1. Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 375. ISBN 978-1416054542.