Difference between revisions of "NUT carcinoma"

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Revision as of 19:48, 15 November 2011

NUT midline carcinoma is a super rare tumour.

General

  • Not specific to any tissue type or organ.[1]
  • Defined by mutation in NUT gene.
    • NUT = Nuclear protein in testis.[2]

Microscopic

Features:[1]

  • Poorly differentiated carcinoma.


Molecular

  • Rearrangement of the NUT gene.[1]
    • Most common: BRD-NUT.[3]

References

  1. ↑ 1.0 1.1 1.2 French, CA. (Nov 2010). "NUT midline carcinoma.". Cancer Genet Cytogenet 203 (1): 16-20. doi:10.1016/j.cancergencyto.2010.06.007. PMID 20951314.
  2. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 608963
  3. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 608749
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