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| *Not the same as ''Bronchiolitis obliterans organizing pneumonia (BOOP)''. | | *Not the same as ''Bronchiolitis obliterans organizing pneumonia (BOOP)''. |
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| ==Idiopathic interstitial pneumonia== | | ==Diffuse lung diseases== |
| *Often [[abbreviated]] '''IIP''', is a term used for a type of [[diffuse lung disease]].
| | {{Main|Diffuse lung diseases}} |
| **Diffuse lung disease is also known as ''interstitial lung disease''.
| | These are also known as ''idiopathic interstitial pneumonias''. |
| ***Diffuse lung disease is probably a better term... as some diseases lumped into this category have involvement of the alveoli, i.e. are not interstitial.
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| ===Histologic classification of IIP===
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| *Can be complex,<ref name="pmid12405906">{{cite journal |author=Nicholson AG |title=Classification of idiopathic interstitial pneumonias: making sense of the alphabet soup |journal=Histopathology |volume=41 |issue=5 |pages=381-91 |year=2002 |month=November |pmid=12405906 |doi= |url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0309-0167&date=2002&volume=41&issue=5&spage=381}}</ref> and the combined efforts of [[clinician]]s, [[radiologist]]s, and [[pathologist]]s can help in the generation of a more specific diagnosis.<ref name="pmid15256390">{{cite journal |author=Flaherty KR, King TE, Raghu G, ''et al'' |title=Idiopathic interstitial pneumonia: what is the effect of a multidisciplinary approach to diagnosis? |journal=Am. J. Respir. Crit. Care Med. |volume=170 |issue=8 |pages=904-10 |year=2004 |month=October |pmid=15256390 |doi=10.1164/rccm.200402-147OC |url=http://ajrccm.atsjournals.org/cgi/pmidlookup?view=long&pmid=15256390}}</ref><ref name="pmid16738191">{{cite journal |author=Kim DS, Collard HR, King TE |title=Classification and natural history of the idiopathic interstitial pneumonias |journal=Proc Am Thorac Soc |volume=3 |issue=4 |pages=285-92 |year=2006 |month=June |pmid=16738191 |doi=10.1513/pats.200601-005TK |url=http://pats.atsjournals.org/cgi/pmidlookup?view=long&pmid=16738191}}</ref>
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| [[Idiopathic]] interstitial pneumonia can be subclassified based on [[histologic]] appearance into the following patterns:<ref>Leslie KO, Wick MR. Practical Pulmonary Pathology: A Diagnostic Approach. Elsevier Inc. 2005. ISBN 978-0-443-06631-3.</ref><ref name=atsers>{{cite journal |author= |title=American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001 |journal=Am. J. Respir. Crit. Care Med. |volume=165 |issue=2 |pages=277-304 |year=2002 |month=January |pmid=11790668 |doi= |url=http://ajrccm.atsjournals.org/cgi/pmidlookup?view=long&pmid=11790668}}</ref>
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| {| class="wikitable"
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| |-
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| ! Histology
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| ! Clinical Correlates
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| ! Associations
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| |-
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| | [[Desquamative interstitial pneumonia]] (DIP)
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| | DIP
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| | Smoking
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| |-
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| | [[Diffuse alveolar damage]] (DAD)
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| | [[ARDS]], [[acute interstitial pneumonia|AIP]], [[Transfusion related acute lung injury|TRALI]]
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| | ARDS: trauma, infection; TRALI: blood transfusion; AIP: viral (???)
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| |-
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| | [[Nonspecific interstitial pneumonia]] (NSIP)
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| | NSIP
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| | ???
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| |-
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| | [[Respiratory bronchiolitis]]
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| | [[Respiratory bronchiolitis-associated interstitial lung disease|RB-ILD]]
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| | Smoking
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| |-
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| | [[Usual interstitial pneumonia]] (UIP)
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| | [[collagen vascular disease|CVD]], [[idiopathic pulmonary fibrosis|IPF]], [[drug toxicity]], [[pneumoconiosis]]
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| | Allergen (hypersensitivity pneumonitis), idiopathic, autoimmune
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| |-
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| | [[Organizing pneumonia]]
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| | [[Cryptogenic organizing pneumonia]]
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| | autoimmune (???)
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| |-
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| | [[Lymphoid interstitial pneumonia]] (LIP)
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| | LIP
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| | Viral/autoimmune
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| |}
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| ARDS = adult respiratory distress syndrome, AIP = acute interstitial pneumonia, TRALI = transfusion related acute lung injury, CVD = collagen vascular disease, IPF = idiopathic pulmonary fibrosis.
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| Notes:
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| *''Usual interstitial pneumonia'' is the most common type of ILD.<ref name="pmid16738196">{{cite journal |author=Visscher DW, Myers JL |title=Histologic spectrum of idiopathic interstitial pneumonias |journal=Proc Am Thorac Soc |volume=3 |issue=4 |pages=322-9 |year=2006 |month=June |pmid=16738196 |doi=10.1513/pats.200602-019TK |url=http://pats.atsjournals.org/cgi/pmidlookup?view=long&pmid=16738196}}</ref>
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| ==Fibrosis== | | ==Fibrosis== |