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Difference between revisions of "Salivary glands"
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HaNP
(HaNP) |
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==Overview== | ==Overview== | ||
===Benign tumours=== | ===Benign tumours=== | ||
'''Tabular form - adapted from Thompson<ref> | '''Tabular form - adapted from Thompson<ref>{{Ref HaNP|295-319}}</ref>''' | ||
{| class="wikitable" | {| class="wikitable" | ||
| | | | ||
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===Malignant tumours=== | ===Malignant tumours=== | ||
'''Tabular form - adapted from Thompson<ref> | '''Tabular form - adapted from Thompson<ref>{{Ref HaNP|325-357}}</ref>''' | ||
{| class="wikitable" | {| class="wikitable" | ||
| || '''Architecture''' || '''Morphology''' || '''Cell borders''' || '''Cytoplasm''' || '''Nucleus''' || '''DDx''' || '''Other''' | | || '''Architecture''' || '''Morphology''' || '''Cell borders''' || '''Cytoplasm''' || '''Nucleus''' || '''DDx''' || '''Other''' | ||
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==Pleomorphic adenoma== | ==Pleomorphic adenoma== | ||
===Epidemiology=== | ===Epidemiology=== | ||
Features:<ref> | Features:<ref name=Ref_HaNP295>{{Ref HaNP|295}}</ref> | ||
*Very common - approx. 60% of parotid gland tumours | *Very common - approx. 60% of parotid gland tumours | ||
===Histology=== | ===Histology=== | ||
Features:<ref> | Features:<ref name=Ref_HaNP295>{{Ref HaNP|295}}</ref> | ||
*Proliferation of myoepithelium and epithelium in mesenchymal stroma. | *Proliferation of myoepithelium and epithelium in mesenchymal stroma. | ||
*Mesenchymal stroma - key feature. | *Mesenchymal stroma - key feature. | ||
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*Look for, i.e. rule-out, poorly differentiated carcinoma: ''carcinoma ex pleomorphic adenoma''. | *Look for, i.e. rule-out, poorly differentiated carcinoma: ''carcinoma ex pleomorphic adenoma''. | ||
IHC: S-100+, SMA+, GFAP+. | IHC: S-100 +ve, SMA +ve, GFAP +ve. | ||
==Basal cell adenoma== | ==Basal cell adenoma== | ||