Difference between revisions of "Intranodal palisaded myofibroblastoma"
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Revision as of 03:09, 4 October 2011
Intranodal palisaded myofibroblastoma, abbreviated IPM, is a rare tumour that classically presents as an inguinal mass.[1]
General
- Rare.
- Male:female = 2:1.
- Adults - middle age.
Microscopic
Features:
- Rim of peripheral lymphoid tissue.
- spindle cells with nuclear palisading
- RBC extravasation/hemorrhage.
- Amianthoid fibers
- intracellular and extracellular fuchsinophilic bodies that stain positive for smooth muscle actin.
DDx:
Image:
IHC
- SMA +ve.
- Cyclin D1 +ve.
Other:
- S100 -ve
- Excludes schwannoma.
- GFAP -ve.
- CD34 -ve.
- Desmin -ve
- Ki-67 - low.
See also
References
- ↑ Nguyen, T.; Eltorky, MA. (Feb 2007). "Intranodal palisaded myofibroblastoma.". Arch Pathol Lab Med 131 (2): 306-10. doi:10.1043/1543-2165(2007)131[306:IPM]2.0.CO;2. PMID 17284119.