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Difference between revisions of "Vasculitides"
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update refs - PBoD
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==Takayasu's arteritis== | ==Takayasu's arteritis== | ||
===General=== | ===General=== | ||
Features:<ref>PBoD | Features:<ref name=Ref_PBoD538>{{Ref PBoD|538}}</ref> | ||
*Disease of medium/large arteries. | *Disease of medium/large arteries. | ||
**Classically involves the aortic arch (leading to decreased pulses in the upper limbs). | **Classically involves the aortic arch (leading to decreased pulses in the upper limbs). | ||
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref>PBoD | Features:<ref name=Ref_PBoD538>{{Ref PBoD|538}}</ref> | ||
*Adventitial mononuclear infiltrate with perivascular cuffing of the vasa vasorum. | *Adventitial mononuclear infiltrate with perivascular cuffing of the vasa vasorum. | ||
*Mononuclear inflammation in media. | *Mononuclear inflammation in media. | ||
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Notes: | Notes: | ||
*Pulmonary hemorrhage syndromes:<ref>PBoD | *Pulmonary hemorrhage syndromes:<ref name=Ref_PBoD745>{{Ref PBoD|745}}</ref> | ||
**Goodpasture syndrome. | **Goodpasture syndrome. | ||
**Idiopathic pulmonary hemosiderosis. | **Idiopathic pulmonary hemosiderosis. | ||
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Granulomas typically poorly formed.<ref>PBoD | *Granulomas typically poorly formed.<ref name=Ref_PBoD747>{{Ref PBoD|747}}</ref> | ||
Image: [http://www.flickr.com/photos/pulmonary_pathology/3734403695/ Wegener's granulomatosis (flickr.com)]. | Image: [http://www.flickr.com/photos/pulmonary_pathology/3734403695/ Wegener's granulomatosis (flickr.com)]. | ||