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Difference between revisions of "Kidney tumours"
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→Clear cell renal cell carcinoma
| Line 363: | Line 363: | ||
Clear cell vs. chromophobe: | Clear cell vs. chromophobe: | ||
*Chromophobe: "translucent" (NOT quite clear), reticulated, Hale's colloidal iron stain+, CK7+ (cell membrane). | *Chromophobe: "translucent" (NOT quite clear), reticulated, Hale's colloidal iron stain+, CK7+ (cell membrane). | ||
==Multilocular cystic renal cell carcinoma== | |||
===General=== | |||
*No recurrences or metastasis in the literature.<ref name=Ref_WMSP292>{{Ref WMSP|292}}</ref> | |||
**This makes one wonder... is it really cancer. | |||
*Case report rare.<ref name=pmid21366448>{{Cite journal | last1 = Agarwal | first1 = S. | last2 = Agrawal | first2 = U. | last3 = Mohanty | first3 = NK. | last4 = Saxena | first4 = S. | title = Multilocular cystic renal cell carcinoma: a case report of a rare entity. | journal = Arch Pathol Lab Med | volume = 135 | issue = 3 | pages = 290-2 | month = Mar | year = 2011 | doi = 10.1043/2010-0243-LE.1 | PMID = 21366448 }}</ref> | |||
===Gross=== | |||
Features:<ref name=Ref_WMSP292>{{Ref WMSP|292}}</ref> | |||
*Cystic with thin septa. | |||
*Well circumscribed. | |||
Note: | |||
*This tumour, radiologically, can often be separated from other cystic tumours.<ref name=pmid21722289>{{Cite journal | last1 = You | first1 = D. | last2 = Shim | first2 = M. | last3 = Jeong | first3 = IG. | last4 = Song | first4 = C. | last5 = Kim | first5 = JK. | last6 = Ro | first6 = JY. | last7 = Hong | first7 = JH. | last8 = Ahn | first8 = H. | last9 = Kim | first9 = CS. | title = Multilocular cystic renal cell carcinoma: clinicopathological features and preoperative prediction using multiphase computed tomography. | journal = BJU Int | volume = | issue = | pages = | month = Jul | year = 2011 | doi = 10.1111/j.1464-410X.2011.10247.x | PMID = 21722289 }}</ref> | |||
===Microscopic=== | |||
Features:<ref name=Ref_WMSP292>{{Ref WMSP|292}}</ref> | |||
*Polygonal cells within the septa. | |||
*Clear cytoplasm. | |||
*+/-Calcification (common). | |||
DDx: | |||
*Cystic renal disease with macrophages in the septa. | |||
*Cystic clear cell renal cell carcinoma. | |||
===IHC=== | |||
*EMA +ve. | |||
*Keratins +ve. | |||
*CD68 -ve. | |||
==Papillary renal cell carcinoma== | ==Papillary renal cell carcinoma== | ||