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Difference between revisions of "Pediatric kidney tumours"
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→Clear cell sarcoma of the kidney
m (→Microscopic) |
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| Line 161: | Line 161: | ||
*Indistinct cell borders/cytoplasm; clear background. | *Indistinct cell borders/cytoplasm; clear background. | ||
*No nucleoli. | *No nucleoli. | ||
==Renal rhabdoid tumour== | |||
*[[AKA]] ''rhabdoid tumour of the kidney'', abbreviated ''RTK''. | |||
===General=== | |||
*Similar to ''[[extrarenal malignant rhabdoid tumour]]''.<ref name=Ref_WMSP284>{{Ref WMSP|284}}</ref> | |||
*Arises from renal medulla. | |||
*May be associated with a CNS tumour. | |||
===Microscopic=== | |||
Features:<ref name=Ref_WMSP627>{{Ref WMSP|627}}</ref><ref name=Ref_WMSP284>{{Ref WMSP|284}}</ref> | |||
*Variable architecture. | |||
*Round cells. | |||
*Abundant cytoplasm with eosinophilic inclusions. | |||
*Eccentric vesicular nucleus. | |||
*Prominent [[nucleolus]] -- '''key feature'''. | |||
===IHC=== | |||
*INI1 -ve. | |||
==Renal cell carcinoma== | |||
===General=== | |||
*Similar to in adults. | |||
*Clear cell RCC not common - a tumour with the clear cell histomorphology is more often a ''renal tumour with a Xp11.2 translocation''. | |||
====Papillary RCC==== | |||
:See: ''[[Renal_cell_carcinoma|(adult) renal cell carcinoma]]''. | |||
*Most common form of RCC in children. | |||
====Clear cell RCC==== | |||
:See: ''[[Renal_cell_carcinoma|(adult) renal cell carcinoma]]''. | |||
==See also== | ==See also== | ||