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Difference between revisions of "Prostate gland"
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m
→Prostate: note about tufted
(→Normal: divide more) |
m (→Prostate: note about tufted) |
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| Line 9: | Line 9: | ||
*Luminal epithelium often clear. | *Luminal epithelium often clear. | ||
*Single nucleus. | *Single nucleus. | ||
Benign normal: | Benign normal: | ||
| Line 21: | Line 17: | ||
**Very common. | **Very common. | ||
**These should be differentiated from ''eosinophilic proteinaceous debris'' - which is associated with cancer. | **These should be differentiated from ''eosinophilic proteinaceous debris'' - which is associated with cancer. | ||
Negatives: | |||
*No nucleoli present (if you see nuclei think: cancer, HGPIN, reactive changes, basal cell hyperplasia). | |||
*No mitoses - these are uncommon... even in high grade prostate cancer. | |||
Notes: | |||
*Tufted epithelium is a strong indicator of benignancy; however two uncommon prostate cancer typically have tufted epithelium: | |||
**Pseudohyperplastic adenocarcinoma. | |||
**Foamy gland carcinoma. | |||
====IHC of normal prostate==== | ====IHC of normal prostate==== | ||