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Difference between revisions of "Dermatologic neoplasms"
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Dermatologic neoplasms (view source)
Revision as of 17:50, 4 September 2011
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_PBoD8_1180-1>{{Ref PBoD8|1180-1}}</ref><ref name=Ref_Derm390>{{Ref Derm|390}}</ref> | Features:<ref name=Ref_PBoD8_1180-1>{{Ref PBoD8|1180-1}}</ref><ref name=Ref_Derm390>{{Ref Derm|390}}</ref> | ||
#Basaloid cells - similar in appearance to basal cells: | |||
#*Moderate blue/grey cytoplasm. | |||
#*Dark ovoid/ellipsoid nucleus with uniform chromatin. | |||
#Palisading of cells at the edge of the cell nests. | |||
#Artefactual separation of cells (forming the nests) from the underlying stroma - '''key feature'''. | |||
#Surrounded by blue (myxoid) stroma - '''key feature'''. | |||
May be present:<ref name=Ref_Derm390>{{Ref Derm|390}}</ref> | |||
*Dystrophic calcification. | |||
*[[Amyloid]]. | |||
*Inflammation. | |||
Notes: | Notes: | ||
*Palisading = the long axes of the cells are alined and the axes are perpendicular to the interface between the (basaloid cell) nests and stroma. | *Palisading = the long axes of the cells are alined and the axes are perpendicular to the interface between the (basaloid cell) nests and stroma. | ||
*Key elements in a list: Artefactual clefting (of nests), Basaloid cells, Peripheral palisading, Myxoid stroma. | *Key elements in a list: Artefactual clefting (of nests), Basaloid cells, Peripheral palisading, Myxoid stroma. | ||
**Memory device ''PAM'': palisading, artefactual clefts, myxoid stroma. | |||
DDx: | DDx: | ||
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**[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/basal_cell_carcinoma_high_power.jpg BCC (ucsf.edu)].<ref>URL: [http://missinglink.ucsf.edu/lm/DermatologyGlossary/basal_cell_carcinoma.html http://missinglink.ucsf.edu/lm/DermatologyGlossary/basal_cell_carcinoma.html]. Accessed on: 4 September 2011.</ref> | **[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/basal_cell_carcinoma_high_power.jpg BCC (ucsf.edu)].<ref>URL: [http://missinglink.ucsf.edu/lm/DermatologyGlossary/basal_cell_carcinoma.html http://missinglink.ucsf.edu/lm/DermatologyGlossary/basal_cell_carcinoma.html]. Accessed on: 4 September 2011.</ref> | ||
====Subtypes==== | ====Subtypes/unique features==== | ||
Many patterns exist:<ref name=Ref_Derm392-5>{{Ref Derm|392-5}}</ref> | Many patterns exist:<ref name=Ref_Derm392-5>{{Ref Derm|392-5}}</ref> | ||
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