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Difference between revisions of "Peripheral nerve sheath tumours"
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Peripheral nerve sheath tumours (view source)
Revision as of 15:37, 31 August 2011
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==Neurofibroma== | ==Neurofibroma== | ||
===General=== | ===General=== | ||
*May be a part of [[neurofibromatosis]] 1. | *May be a part of [[neurofibromatosis]] 1 (NF1). | ||
*Composed of Schwann cells, axons, fibrous material.<ref name=pmid17893219/> | *Composed of Schwann cells, axons, fibrous material.<ref name=pmid17893219/> | ||
Classification:<ref name=pmid15486243>{{Cite journal | last1 = Wilkinson | first1 = LM. | last2 = Manson | first2 = D. | last3 = Smith | first3 = CR. | title = Best cases from the AFIP: plexiform neurofibroma of the bladder. | journal = Radiographics | volume = 24 Suppl 1 | issue = | pages = S237-42 | month = Oct | year = 2004 | doi = 10.1148/rg.24si035170 | PMID = 15486243 }}</ref> | |||
#Localized - sporatic. | |||
#Diffuse - usu. poorly defined, young adults and children; sporatic. | |||
#Plexiform - assoc. with NF1. | |||
===Gross/radiologic=== | |||
Gross features (plexiform NF):<ref name=pmid15486243>{{Cite journal | last1 = Wilkinson | first1 = LM. | last2 = Manson | first2 = D. | last3 = Smith | first3 = CR. | title = Best cases from the AFIP: plexiform neurofibroma of the bladder. | journal = Radiographics | volume = 24 Suppl 1 | issue = | pages = S237-42 | month = Oct | year = 2004 | doi = 10.1148/rg.24si035170 | PMID = 15486243 }}</ref> | |||
*"Bag of worms" appearance. | |||
Radiologic:<ref name=pmid15486243/> | |||
*Fusiform mass. | |||
===Microscopic=== | ===Microscopic=== | ||
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Image: | Image: | ||
*[http://commons.wikimedia.org/wiki/File:Neurofibroma_(1).jpg Neurofibroma - low mag. (WC)]. | *[[WC]]: | ||
*[http://commons.wikimedia.org/wiki/File:Neurofibroma_(2).jpg Neurofibroma - high mag. (WC)]. | **[http://commons.wikimedia.org/wiki/File:Neurofibroma_(1).jpg Neurofibroma - low mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Neurofibroma_(3).jpg Neurofibroma - high mag. (WC)]. | **[http://commons.wikimedia.org/wiki/File:Neurofibroma_(2).jpg Neurofibroma - high mag. (WC)]. | ||
**[http://commons.wikimedia.org/wiki/File:Neurofibroma_(3).jpg Neurofibroma - high mag. (WC)]. | |||
www: | |||
*[http://radiographics.rsna.org/content/24/suppl_1/S237/F9.expansion.html Plexiform neurofibroma (rsna.org)]. | |||
*[http://radiographics.rsna.org/content/24/suppl_1/S237/F10.expansion.html Plexiform neurofibroma (rsna.org)]. | |||
===IHC=== | ===IHC=== | ||