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*Moderate vaginal intraepithelial neoplasia (VAIN II). | *Moderate vaginal intraepithelial neoplasia (VAIN II). | ||
*Severe vaginal intraepithelial neoplasia (VAIN III). | *Severe vaginal intraepithelial neoplasia (VAIN III). | ||
==Viral infections== | |||
===General=== | |||
*Cannot differentiate HSV1, HSV2, VZV using H&E.<ref name=herpes>URL: [http://missinglink.ucsf.edu/lm/DermatologyGlossary/herpes_simplex.html http://missinglink.ucsf.edu/lm/DermatologyGlossary/herpes_simplex.html]. Accessed on: 30 August 2011.</ref> | |||
===Microscopic=== | |||
Features:<ref name=herpes/> | |||
*Keratinocytes enlargement + acanthosis. | |||
**Intraepidermal vesicles & bullae. | |||
*Nuclear changes - 3 Ms: | |||
*#Moulding of nuclei. | |||
*#Margination of chromatin. | |||
*#Multinucleation. | |||
*Nuclei have "steel gray" colour. | |||
Images: | |||
*[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/herpes_high_power.jpg Herpes (ucsf.edu)]. | |||
*[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/herpes_low_power.jpg Herpes - skin (ucsf.edu)]. | |||
==See also== | ==See also== |
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