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(→Inflammatory conditions: psoriasis) |
(→Lichen planus: more) |
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*6 Ps: pruritic (itchy), purple, polygonal, planar papules and plaques. | *6 Ps: pruritic (itchy), purple, polygonal, planar papules and plaques. | ||
=== | ===Gross=== | ||
*Wickham striae = white lines/dots. | |||
**Due to hypergranulosis. | |||
===Microscopic=== | |||
Features:<ref>URL: [http://emedicine.medscape.com/article/1078327-overview http://emedicine.medscape.com/article/1078327-overview]. Accessed on: 11 September 2010.</ref><ref name=Ref_PBoD8_1192>{{Ref PBoD8|1192}}</ref> | Features:<ref>URL: [http://emedicine.medscape.com/article/1078327-overview http://emedicine.medscape.com/article/1078327-overview]. Accessed on: 11 September 2010.</ref><ref name=Ref_PBoD8_1192>{{Ref PBoD8|1192}}</ref> | ||
*Loss of basal cells (stratum basale) -- '''key feature'''. | *Loss of basal cells (stratum basale) -- '''key feature'''. | ||
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*Hypergranulosis; stratum granulosum thickened (grossly seen as "Wickham stria" = white lines). | *Hypergranulosis; stratum granulosum thickened (grossly seen as "Wickham stria" = white lines). | ||
*Hyperkeratosis; stratum corneum thickened. | *Hyperkeratosis; stratum corneum thickened. | ||
*Necrotic basal cell in dermis = colloid bodies = Civatte bodies.<ref>{{Ref PCPBoD8_604}}</ref> | |||
Notes: | Notes: | ||
*Hyperkeratosis and hypergranulosis are not seen in [[erythema multiforme]]. | *Hyperkeratosis and hypergranulosis are not seen in [[erythema multiforme]]. | ||
*Colloid bodies = cytoid bodies = Civatte bodies = hyaline bodies = apoptotic bodies.<ref>URL: [http://www.careforumwales.org/cell-carcinoma/histopathologic-terminology.html http://www.careforumwales.org/cell-carcinoma/histopathologic-terminology.html]. Accessed on: 28 August 2011.</ref> | |||
**DDx: systemic lupus erythematosus, lichen planus, and [[graft-versus-host disease]]. | |||
Images: | Images: |
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