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Difference between revisions of "Uterine tumours"
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→Adenosarcoma: more
m (→Microscopic) |
m (→Adenosarcoma: more) |
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==Adenosarcoma== | ==Adenosarcoma== | ||
===General=== | ===General=== | ||
Features:<ref name=pmid20179434>{{Cite journal | last1 = McCluggage | first1 = WG. | title = Mullerian adenosarcoma of the female genital tract. | journal = Adv Anat Pathol | volume = 17 | issue = 2 | pages = 122-9 | month = Mar | year = 2010 | doi = 10.1097/PAP.0b013e3181cfe732 | PMID = 20179434 }}</ref> | |||
*Uncommon. | *Uncommon. | ||
*May prolapse through cervical os and thus present as [[cervical polyp]]. | |||
*Most commonly uterine corpus, occasionally cervix and ovary, rarely in the vagina, fallopian tube, peritoneal surfaces, intestine. | |||
*Typically 30-40 years old. | |||
Treatment: | |||
*TAH | *TAH-BSO. | ||
**Tumours are estrogen responsive. | |||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_PBoD1089>{{Ref PBoD|1089}}</ref> | Features:<ref name=Ref_PBoD1089>{{Ref PBoD|1089}}</ref><ref name=pmid20179434/> | ||
*"Malignant stroma" - '''key feature'''. | *"Malignant stroma" - '''key feature'''. | ||
**Stromal nuclear pleomorphism. | **Stromal nuclear pleomorphism - usu. low grade. | ||
**WHO criteria: 2+ mitoses / 10 HPF -- definition suffers from [[HPFitis]]. | |||
*Benign glands with an abnormal shape. | *Benign glands with an abnormal shape. | ||
*"Cambium layer" = increased cellularity around the epithelial elements.<ref name=pmid20179434/><ref name=medilexicon_cambium/> | |||
DDx: | DDx: | ||
*Benign polyp. | *Benign polyp. | ||
Notes: | |||
*''Cambium layer'' - seen in: adenosarcoma, botryoid [[RMS]].<ref name=medilexicon_cambium>URL: [http://www.medilexicon.com/medicaldictionary.php?t=48297 http://www.medilexicon.com/medicaldictionary.php?t=48297]. Accessed on: 9 August 2011.</ref> | |||
==Leiomyocarcoma== | ==Leiomyocarcoma== | ||