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Difference between revisions of "Lymphoma"
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→Microscopic: more
(→Anaplastic large cell lymphoma: tweak) |
(→Microscopic: more) |
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features:<ref></ref> | ||
*Large cells with eosinophilic cytoplasm. | *Large cells with eosinophilic cytoplasm. | ||
*Usually appear cohesive. | *Usually appear cohesive. | ||
| Line 409: | Line 409: | ||
*"Wreath cells" - large (multinucleated) cells with (morphologically) one toroidal-shaped nucleus - '''key feature'''. | *"Wreath cells" - large (multinucleated) cells with (morphologically) one toroidal-shaped nucleus - '''key feature'''. | ||
**C-shaped nuclei may be present suggestive of wreath cells. | **C-shaped nuclei may be present suggestive of wreath cells. | ||
**[[AKA]] "Hallmark cells". (???) | |||
***"Hallmark cells" = horseshoe-shaped or donut-shaped nucleus with an eosinophilic paranuclear region.<ref name=pmid17941004>{{Cite journal | last1 = Rapkiewicz | first1 = A. | last2 = Wen | first2 = H. | last3 = Sen | first3 = F. | last4 = Das | first4 = K. | title = Cytomorphologic examination of anaplastic large cell lymphoma by fine-needle aspiration cytology. | journal = Cancer | volume = 111 | issue = 6 | pages = 499-507 | month = Dec | year = 2007 | doi = 10.1002/cncr.23120 | PMID = 17941004 | url=http://onlinelibrary.wiley.com/doi/10.1002/cncr.23120/full}}</ref><ref name=pmid12419758>{{Cite journal | last1 = Ponzoni | first1 = M. | last2 = Terreni | first2 = MR. | last3 = Ciceri | first3 = F. | last4 = Ferreri | first4 = AJ. | last5 = Gerevini | first5 = S. | last6 = Anzalone | first6 = N. | last7 = Valle | first7 = M. | last8 = Pizzolito | first8 = S. | last9 = Arrigoni | first9 = G. | title = Primary brain CD30+ ALK1+ anaplastic large cell lymphoma ('ALKoma'): the first case with a combination of 'not common' variants. | journal = Ann Oncol | volume = 13 | issue = 11 | pages = 1827-32 | month = Nov | year = 2002 | doi = | PMID = 12419758 }}</ref>) | |||
===IHC=== | ===IHC=== | ||