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Difference between revisions of "Uterine tumours"
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→Carcinosarcoma: more
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(→Carcinosarcoma: more) |
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==Carcinosarcoma== | ==Carcinosarcoma== | ||
* AKA | * AKA ''malignant mixed muellerian tumour'', abbreviated ''MMMT''. | ||
===General=== | |||
* Associated with previous radiation exposure. | |||
* | |||
* Metstasize as adenocarcinoma. | * Metstasize as adenocarcinoma. | ||
* Aggressive/poor prognosis;<ref name=pmid15688674>{{Cite journal | last1 = Ivy | first1 = JJ. | last2 = Unger | first2 = JB. | title = Malignant mixed mullerian sarcomas of the uterus--the LSUHSC Shreveport experience. | journal = J La State Med Soc | volume = 156 | issue = 6 | pages = 324-6 | month = | year = | doi = | PMID = 15688674 }}</ref> in one series 5 year survival ~= 30-35%.<ref name=pmid14967435>{{Cite journal | last1 = Callister | first1 = M. | last2 = Ramondetta | first2 = LM. | last3 = Jhingran | first3 = A. | last4 = Burke | first4 = TW. | last5 = Eifel | first5 = PJ. | title = Malignant mixed Müllerian tumors of the uterus: analysis of patterns of failure, prognostic factors, and treatment outcome. | journal = Int J Radiat Oncol Biol Phys | volume = 58 | issue = 3 | pages = 786-96 | month = Mar | year = 2004 | doi = 10.1016/S0360-3016(03)01561-X | PMID = 14967435 }}</ref> | |||
*Considered to be a poorly differentiated endometrial carcinoma with metaplastic changes.<ref name=pmid19853898>{{Cite journal | last1 = D'Angelo | first1 = E. | last2 = Prat | first2 = J. | title = Uterine sarcomas: a review. | journal = Gynecol Oncol | volume = 116 | issue = 1 | pages = 131-9 | month = Jan | year = 2010 | doi = 10.1016/j.ygyno.2009.09.023 | PMID = 19853898 }}</ref> | |||
*Case reports of MMMT in [[ovary]] and [[fallopian tube]]. | |||
===Microscopic=== | |||
Features:<ref name=Ref_WMSP428>{{Ref WMSP|428}}</ref> | |||
*Biphasic tumour: | |||
*#Malignant glandular component (adenocarcinoma). | |||
*#Malignant stromal component (one of the following): | |||
*#*Skeletal muscle. | |||
*#*Smooth muscle. | |||
*#*Cartilage. | |||
*#*Bone. | |||
*#*Undifferentiated sarcoma. | |||
Image: | |||
[http://commons.wikimedia.org/wiki/File:MalignantMixedMullerianTumor.JPG MMMT (WC)]. | |||
==Adenosarcoma== | ==Adenosarcoma== | ||