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===General=== | ===General=== | ||
*Rare. | *Rare. | ||
* | *Associated with sickle cell trait (heterozygotes for the sickle cell allele).<ref name=pmid7528470>{{cite journal |author=Davis CJ, Mostofi FK, Sesterhenn IA |title=Renal medullary carcinoma. The seventh sickle cell nephropathy |journal=Am. J. Surg. Pathol. |volume=19 |issue=1 |pages=1–11 |year=1995 |month=January |pmid=7528470 |doi= |url=}}</ref> | ||
===Gross=== | ===Gross=== | ||
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Features:<ref name=pmid7528470/><ref name=pmid17643096>{{cite journal |author=Watanabe IC, Billis A, Guimarães MS, ''et al.'' |title=Renal medullary carcinoma: report of seven cases from Brazil |journal=Mod. Pathol. |volume=20 |issue=9 |pages=914–20 |year=2007 |month=September |pmid=17643096 |doi=10.1038/modpathol.3800934 |url=}}</ref> | Features:<ref name=pmid7528470/><ref name=pmid17643096>{{cite journal |author=Watanabe IC, Billis A, Guimarães MS, ''et al.'' |title=Renal medullary carcinoma: report of seven cases from Brazil |journal=Mod. Pathol. |volume=20 |issue=9 |pages=914–20 |year=2007 |month=September |pmid=17643096 |doi=10.1038/modpathol.3800934 |url=}}</ref> | ||
*Variable architecture: | *Variable architecture: | ||
**Reticular - classic. | |||
**[[Adenoid cystic carcinoma]]-like appearance: | **[[Adenoid cystic carcinoma]]-like appearance: | ||
***Cystic spaces. | ***Cystic spaces. | ||
**Yolk sac-like. | **Yolk sac-like. | ||
**Tubular. | **Tubular. | ||
*Desmoplastic stroma. | *Desmoplastic stroma - prominent. | ||
*Inflammation: | *Inflammation: | ||
**Lymphocytes. | **Lymphocytes. | ||
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*Renal infarction. | *Renal infarction. | ||
*Pyelonephritis. | *Pyelonephritis. | ||
Image: | |||
*[http://www.nature.com/modpathol/journal/v20/n9/fig_tab/3800934f3.html#figure-title RMC (nature.com)]. | |||
=Pediatric= | =Pediatric= |
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