Difference between revisions of "ALK translocation renal cell carcinoma"

ALK translocation renal cell carcinoma (view source)

107 bytes added , 21:37, 26 September 2025

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 *[[SMARCB1]] normal nuclear staining.{{fact}}
-‡ There are different clones for ALK.  The ALK clone for lung cancer (e.g. D5F3) should be used.<ref>{{cite journal |authors=Kai K, Tobu S, Kido S, Mikami S, Takeuchi K, Dobashi A, Togashi Y, Noguchi M, Aishima S |title=ALK rearrangement-associated renal cell carcinoma morphologically mimicking mucinous tubular and spindle cell carcinoma: a case report |journal=Diagn Pathol |volume=17 |issue=1 |pages=52 |date=June 2022 |pmid=35718773 |pmc=9206751 |doi=10.1186/s13000-022-01238-z |url=}}</ref>
+‡ There are different clones for ALK. They may be called ''ALK1'' (used of lymphoma) and ''L-ALK'' (used of lung cancer).  In the context of RCC, the ALK clone for lung cancer (e.g. D5F3) should be used.<ref>{{cite journal |authors=Kai K, Tobu S, Kido S, Mikami S, Takeuchi K, Dobashi A, Togashi Y, Noguchi M, Aishima S |title=ALK rearrangement-associated renal cell carcinoma morphologically mimicking mucinous tubular and spindle cell carcinoma: a case report |journal=Diagn Pathol |volume=17 |issue=1 |pages=52 |date=June 2022 |pmid=35718773 |pmc=9206751 |doi=10.1186/s13000-022-01238-z |url=}}</ref>
 ==Molecular==