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Difference between revisions of "Testis"
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→IHC for GCTs
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<gallery> | <gallery> | ||
Image:Leydig_cells_-_very_high_mag.jpg | Leydig cells - very high mag. (WC/Nephron) | Image:Leydig_cells_-_very_high_mag.jpg | Leydig cells - very high mag. (WC/Nephron) | ||
</gallery> | </gallery> | ||
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www: | www: | ||
*[http://www.webpathology.com/image.asp?case=27&n=5 Rete testis (webpathology.com)]. | *[http://www.webpathology.com/image.asp?case=27&n=5 Rete testis (webpathology.com)]. | ||
====Associated structures==== | |||
====Epididymis==== | |||
{{main|Epididymis}} | |||
*[[Epididymis]] - stores the sperm. | |||
**Pseudostratified epithelium with [[cilia]]. | |||
Image: | |||
<gallery> | |||
Image:Epididymis_high_mag.jpg |[[Micrograph]] of an epididymis. [[H&E stain]]. | |||
</gallery> | |||
====Appendix of testis==== | ====Appendix of testis==== | ||
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**[[Leydig cell tumour]]. | **[[Leydig cell tumour]]. | ||
**[[Sertoli cell tumour]]. | **[[Sertoli cell tumour]]. | ||
===Serum markers of testicular tumours=== | |||
*AFP (alpha-fetoprotein) | |||
*hCG. | |||
*LDH (lactate dehydrogenase). | |||
*M371 (microRNA-371a-3p).<ref name=pmid37568759>{{cite journal |authors=Nestler T, Schoch J, Belge G, Dieckmann KP |title=MicroRNA-371a-3p-The Novel Serum Biomarker in Testicular Germ Cell Tumors |journal=Cancers (Basel) |volume=15 |issue=15 |pages= |date=August 2023 |pmid=37568759 |pmc=10417034 |doi=10.3390/cancers15153944 |url=}}</ref> | |||
===IHC for GCTs=== | ===IHC for GCTs=== | ||
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*CD30 - embryonal carcinoma. | *CD30 - embryonal carcinoma. | ||
*[[D2-40]] - seminoma. | *[[D2-40]] - seminoma. | ||
*SALL4 - most [[germ cell tumour]]s. | |||
===Tabular summary of GCTs=== | ===Tabular summary of GCTs=== | ||