Cutaneous calcinosis: Difference between revisions
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| Caption = Cutaneous calcinosis. [[H&E stain]]. | | Caption = Cutaneous calcinosis. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = cutaneous calcification, calcinosis cutis | ||
| Micro = dermal calcification - usu. well-circumscribed | | Micro = dermal calcification - usu. well-circumscribed | ||
| Subtypes = | | Subtypes = | ||
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| Tx = excision | | Tx = excision | ||
}} | }} | ||
'''Cutaneous calcinosis''', also '''calcinosis cutis''', is calcification of the [[skin]]. It is benign in itself; however, the underlying cause not be. | '''Cutaneous calcinosis''', also '''calcinosis cutis''' and '''cutaneous calcification''', is calcification of the [[skin]]. It is benign in itself; however, the underlying cause may ''not'' be. | ||
==General== | ==General== | ||
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Subtypes:<ref name=emed>URL: [http://emedicine.medscape.com/article/1103137-overview http://emedicine.medscape.com/article/1103137-overview]. Accessed on: 21 September 2011.</ref> | Subtypes:<ref name=emed>URL: [http://emedicine.medscape.com/article/1103137-overview http://emedicine.medscape.com/article/1103137-overview]. Accessed on: 21 September 2011.</ref> | ||
#Dystrophic - due to death of cells; may be related to a tumour. | #Dystrophic - due to death of cells; may be related to a tumour. | ||
#Metastatic - due to chronic renal failure; hyperkalemia; paraneoplastic phenomenon. | #Metastatic - due to [[chronic renal failure]]; hyperkalemia; paraneoplastic phenomenon. | ||
#Iatrogenic - post surgical. | #Iatrogenic - post surgical. | ||
#Idiopathic. | #Idiopathic. | ||
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===Micro=== | ===Micro=== | ||
The sections show | The sections show calcifications surrounded by macrophages and giant cells. No nuclear atypia is apparent. The overlying epidermis is unremarkable. | ||
====Without epidermis==== | |||
The sections show dermal/subcutaneous calcifications surrounded by fibrosis, macrophages and giant cells. No nuclear atypia is apparent. Overlying epidermis is absent. | |||
==See also== | ==See also== | ||
*[[Non-malignant skin disease]]. | *[[Non-malignant skin disease]]. | ||
*[[Heterotopic ossification]]. | |||
*[[Scrotolith]]. | |||
==References== | ==References== | ||