Succinate dehydrogenase-deficient renal cell carcinoma: Difference between revisions

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| LMDDx      = [[renal oncocytoma]], [[chromophobe renal cell carcinoma]], [[clear cell renal cell carcinoma]], other [[renal tumours with eosinophilic cytoplasm]]
| LMDDx      = [[renal oncocytoma]], [[chromophobe renal cell carcinoma]], [[clear cell renal cell carcinoma]], other [[renal tumours with eosinophilic cytoplasm]]
| Stains    =  
| Stains    =  
| IHC        = SDHB -ve, CK7 -ve, CD117 -ve, PAX8 +ve
| IHC        = SDHB -ve, CK7 -ve, CD117 -ve, PAX8 +ve, CA9 -ve
| EM        =
| EM        =
| Molecular  =
| Molecular  =
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'''Succinate dehydrogenase-deficient renal cell carcinoma''', also '''[[succinate dehydrogenase]] renal cell carcinoma''' (abbreviated '''SDH-RCC'''), is a very rare type of [[renal cell carcinoma]].
'''Succinate dehydrogenase-deficient renal cell carcinoma''', also '''[[succinate dehydrogenase]] renal cell carcinoma''' (abbreviated '''SDH-RCC'''), is a very rare type of [[renal cell carcinoma]].


It is grouped in the ''emerging entities'' of the ''[[Vancouver classification|Vancouver modification of the 2004 WHO classification of renal neoplasia]]''.<ref name=pmid24025519>{{Cite journal  | last1 = Srigley | first1 = JR. | last2 = Delahunt | first2 = B. | last3 = Eble | first3 = JN. | last4 = Egevad | first4 = L. | last5 = Epstein | first5 = JI. | last6 = Grignon | first6 = D. | last7 = Hes | first7 = O. | last8 = Moch | first8 = H. | last9 = Montironi | first9 = R. | title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. | journal = Am J Surg Pathol | volume = 37 | issue = 10 | pages = 1469-89 | month = Oct | year = 2013 | doi = 10.1097/PAS.0b013e318299f2d1 | PMID = 24025519 }}</ref>
It is in the 2016 World Health Organization classification of renal neoplasia.


==General==
==General==
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**May be (pseudo)negative in clear cells (as few mitochondria).
**May be (pseudo)negative in clear cells (as few mitochondria).
*CD117 -ve - '''important'''.
*CD117 -ve - '''important'''.
*CA9 -ve.


Others:
Others:
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