49,267
edits
Difference between revisions of "Cardiomyopathy"
Jump to navigation
Jump to search
+BHS
(→Dilated cardiomyopathy: +abbrev.) |
(+BHS) |
||
| (3 intermediate revisions by the same user not shown) | |||
| Line 17: | Line 17: | ||
*Myocarditis - leading cause, usually viral.<ref name=pmid19017683>{{cite journal |author=Luk A, Ahn E, Soor GS, Butany J |title=Dilated cardiomyopathy: a review |journal=J. Clin. Pathol. |volume=62 |issue=3 |pages=219–25 |year=2009 |month=March |pmid=19017683 |doi=10.1136/jcp.2008.060731 |url=}}</ref> | *Myocarditis - leading cause, usually viral.<ref name=pmid19017683>{{cite journal |author=Luk A, Ahn E, Soor GS, Butany J |title=Dilated cardiomyopathy: a review |journal=J. Clin. Pathol. |volume=62 |issue=3 |pages=219–25 |year=2009 |month=March |pmid=19017683 |doi=10.1136/jcp.2008.060731 |url=}}</ref> | ||
*Familial ~ 30% - can be AD with variable penetrance, AR, X-linked. | *Familial ~ 30% - can be AD with variable penetrance, AR, X-linked. | ||
*In the [[forensic pathology|forensic]] context, usually caused by alcoholism.<ref name=Ref_HoFP43>{{Ref HoFP|43}}</ref> | *In the [[forensic pathology|forensic]] context, usually caused by [[alcoholism]].<ref name=Ref_HoFP43>{{Ref HoFP|43}}</ref> | ||
===Microscopic=== | ===Microscopic=== | ||
| Line 104: | Line 104: | ||
===Gross=== | ===Gross=== | ||
Features:<ref name=emedicine1612324>URL: [http://emedicine.medscape.com/article/1612324-overview http://emedicine.medscape.com/article/1612324-overview].</ref> | Features:<ref name=emedicine1612324>URL: [http://emedicine.medscape.com/article/1612324-overview http://emedicine.medscape.com/article/1612324-overview].</ref> | ||
* | *Right ventricular wall thinning/replacement with fat. † | ||
**Especially fat where fat is ''not'' usually seen - posterior RV wall, RVOT. | **Especially fat where fat is ''not'' usually seen - posterior RV wall, RVOT. | ||
*Septum usually has relative sparing | *Septum usually has relative sparing | ||
**Thus, endomyocardial biopsy is ''not'' reliable. | **Thus, endomyocardial biopsy is ''not'' reliable. | ||
*+/-Aneurysms/dilation. | *+/-Aneurysms/dilation. | ||
Note: | |||
*† May involve the left ventricle.<ref name=pmid23761986>{{cite journal |author=Romero J, Mejia-Lopez E, Manrique C, Lucariello R |title=Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC/D): A Systematic Literature Review |journal=Clin Med Insights Cardiol |volume=7 |issue= |pages=97–114 |year=2013 |pmid=23761986 |pmc=3667685 |doi=10.4137/CMC.S10940 |url=}}</ref> | |||
===Microscopic=== | ===Microscopic=== | ||
| Line 119: | Line 122: | ||
*Myocytes have "bubbly" appearance with loss of myofibres and cross-striations. | *Myocytes have "bubbly" appearance with loss of myofibres and cross-striations. | ||
Images | ====Images==== | ||
<gallery> | |||
Image: Arrhythmogenic right ventricular cardiomyopathy - histology.jpg | ARVC. (WC) | |||
</gallery> | |||
=====www===== | |||
*[http://path.upmc.edu/cases/case223.html ARVC - several images (upmc.edu)]. | *[http://path.upmc.edu/cases/case223.html ARVC - several images (upmc.edu)]. | ||
| Line 133: | Line 139: | ||
*Prominent "mesh-like" [[trabeculae]] carnae. | *Prominent "mesh-like" [[trabeculae]] carnae. | ||
**Enlarged intertrabecular recesses.<ref name=pmid2372897>{{cite journal |author=Chin TK, Perloff JK, Williams RG, Jue K, Mohrmann R |title=Isolated noncompaction of left ventricular myocardium. A study of eight cases |journal=Circulation |volume=82 |issue=2 |pages=507–13 |year=1990 |month=August |pmid=2372897 |doi= |url=}}</ref> | **Enlarged intertrabecular recesses.<ref name=pmid2372897>{{cite journal |author=Chin TK, Perloff JK, Williams RG, Jue K, Mohrmann R |title=Isolated noncompaction of left ventricular myocardium. A study of eight cases |journal=Circulation |volume=82 |issue=2 |pages=507–13 |year=1990 |month=August |pmid=2372897 |doi= |url=}}</ref> | ||
==Takotsubo cardiomyopathy== | |||
{{Main|Takotsubo cardiomyopathy}} | |||
*Also known as ''broken heart syndrome''. | |||
==See also== | ==See also== | ||