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Difference between revisions of "Embryonal carcinoma"
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**Iczkowski ''et al.'' suggest it is useful for discriminating from [[seminoma]]. This is somewhat disputed by Lau ''et al.''<ref name=pmid17277761>{{Cite journal | last1 = Lau | first1 = SK. | last2 = Weiss | first2 = LM. | last3 = Chu | first3 = PG. | title = D2-40 immunohistochemistry in the differential diagnosis of seminoma and embryonal carcinoma: a comparative immunohistochemical study with KIT (CD117) and CD30. | journal = Mod Pathol | volume = 20 | issue = 3 | pages = 320-5 | month = Mar | year = 2007 | doi = 10.1038/modpathol.3800749 | PMID = 17277761 }}</ref> | **Iczkowski ''et al.'' suggest it is useful for discriminating from [[seminoma]]. This is somewhat disputed by Lau ''et al.''<ref name=pmid17277761>{{Cite journal | last1 = Lau | first1 = SK. | last2 = Weiss | first2 = LM. | last3 = Chu | first3 = PG. | title = D2-40 immunohistochemistry in the differential diagnosis of seminoma and embryonal carcinoma: a comparative immunohistochemical study with KIT (CD117) and CD30. | journal = Mod Pathol | volume = 20 | issue = 3 | pages = 320-5 | month = Mar | year = 2007 | doi = 10.1038/modpathol.3800749 | PMID = 17277761 }}</ref> | ||
*[[PLAP]] +ve.<ref name=pmid6209917>{{Cite journal | last1 = Jacobsen | first1 = GK. | last2 = Nørgaard-Pedersen | first2 = B. | title = Placental alkaline phosphatase in testicular germ cell tumours and in carcinoma-in-situ of the testis. An immunohistochemical study. | journal = Acta Pathol Microbiol Immunol Scand A | volume = 92 | issue = 5 | pages = 323-9 | month = Sep | year = 1984 | doi = | PMID = 6209917 }}</ref> | *[[PLAP]] +ve.<ref name=pmid6209917>{{Cite journal | last1 = Jacobsen | first1 = GK. | last2 = Nørgaard-Pedersen | first2 = B. | title = Placental alkaline phosphatase in testicular germ cell tumours and in carcinoma-in-situ of the testis. An immunohistochemical study. | journal = Acta Pathol Microbiol Immunol Scand A | volume = 92 | issue = 5 | pages = 323-9 | month = Sep | year = 1984 | doi = | PMID = 6209917 }}</ref> | ||
*CK7 +ve/-ve (~50% have weak staining).<ref name=pmid30359635>{{cite journal |authors=Wegman SJ, Parwani AV, Zynger DL |title=Cytokeratin 7, inhibin, and p63 in testicular germ cell tumor: superior markers of choriocarcinoma compared to β-human chorionic gonadotropin |journal=Hum Pathol |volume=84 |issue= |pages=254–261 |date=February 2019 |pmid=30359635 |doi=10.1016/j.humpath.2018.10.007 |url=}}</ref> | |||
**Seminoma -ve, choriocarcinoma +ve. | |||
==See also== | ==See also== | ||