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[[Image:Gray1136.png|thumb|250px|right|Schematic showing the Bulbourethral gland (Cowper's gland) in relation to other structures. (WC/Gray's Anatomy)]] | |||
'''Bulbourethral gland''', also '''Cowper's gland''', is an accessory gland of the male reproductive system found at the apex of the [[prostate gland]]. It may be confused with [[prostate carcinoma]], especially [[foamy gland carcinoma]]. | |||
==General== | |||
*Mucinous glands at the apex of the [[prostate gland]]. | |||
==Microscopic== | |||
Features:<ref name=pmid9158679>{{Cite journal | last1 = Cina | first1 = SJ. | last2 = Silberman | first2 = MA. | last3 = Kahane | first3 = H. | last4 = Epstein | first4 = JI. | title = Diagnosis of Cowper's glands on prostate needle biopsy. | journal = Am J Surg Pathol | volume = 21 | issue = 5 | pages = 550-5 | month = May | year = 1997 | doi = | PMID = 9158679 }}</ref> | |||
*Lobular glands with abundant pale cytoplasm. | |||
**Resemble (mucinous) [[salivary gland]]s. | |||
*Often assocatiated with skeletal muscle.<ref>URL: [http://webpathology.com/image.asp?case=21&n=4 http://webpathology.com/image.asp?case=21&n=4]. Accessed on: 3 June 2013.</ref> | |||
DDx: | |||
*[[Foamy gland carcinoma]]. | |||
*Mucinous metaplasia of the prostate. | |||
*[[Cowper gland adenocarcinoma]]. | |||
===Images=== | |||
<gallery> | |||
Image: Bulbourethral gland -- intermed mag.jpg | BG - intermed. mag. | |||
Image: Bulbourethral gland -- high mag.jpg | BG - high mag. | |||
Image: Bulbourethral gland -- very high mag.jpg | BG - very high mag. | |||
Image: Bulbourethral gland - alt -- intermed mag.jpg | BG - intermed. mag. | |||
Image: Bulbourethral gland - alt -- high mag.jpg | BG - high mag. | |||
Image: Bulbourethral gland - alt -- very high mag.jpg | BG - very high mag. | |||
</gallery> | |||
www: | |||
*[http://pathology.mc.duke.edu/research/histo_course/mixed_saliv.jpg Mucinous/serous salivary gland (duke.edu)]. | |||
*[http://webpathology.com/image.asp?case=21&n=4 Cowper gland (webpathology.com)]. | |||
==Stains== | |||
*[[Mucicarmine]] +ve. | |||
*[[PAS-D]] +ve. | |||
==IHC== | |||
Features:<ref name=pmid9158679/> | |||
*[[PSAP]] -ve. | |||
*[[PSA]] +ve. | |||
*HMWCK +ve. | |||
==See also== | |||
*[[Prostate gland]]. | |||
*[[Adenosis of the prostate gland]]. | |||
*[[Cowper gland adenocarcinoma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Prostate gland]] |
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