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Difference between revisions of "CSF cytopathology"
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Jensflorian (talk | contribs) (→Cytology: HSV1 encephalitis) |
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==Normal== | ==Normal== | ||
*Paucicellular. | *Paucicellular. | ||
*< | **Acellular specimens common and considered adequate.<ref>{{cite book |author=Mody, Dina R. |title= [https://www.amazon.ca/Diagnostic-Pathology-Cytopathology-Dina-Mody/dp/1931884552/ Diagnostic Cytopathology] |publisher=Elsevier Canada |location= |year=2018 |pages= {{{1|II-3 2}}} |edition=1st |isbn=978-1931884556 |oclc= |doi= |accessdate=}}</ref> | ||
*protein is around 15-40 mg/dl | |||
Gobs of anuclear material: | Gobs of anuclear material: | ||
*Protein vs. white | *Protein vs. white matter. | ||
*Ocassionally arachnoid cap cell- | |||
Bark-like flaky material: | Bark-like flaky material: | ||
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==Hemorrhage== | ==Hemorrhage== | ||
*Xanthochromatous specimen | *Xanthochromatous specimen | ||
**Can be artificial -> due punctuation. | **Can be artificial -> due punctuation injuries or rifampin medication.<ref name="pmid7125611">{{Cite journal | last1 = Liggett | first1 = SB. | last2 = Berger | first2 = JR. | last3 = Hush | first3 = J. | title = Cerebrospinal fluid xanthochromia with rifampin. | journal = Ann Neurol | volume = 12 | issue = 2 | pages = 228-9 | month = Aug | year = 1982 | doi = 10.1002/ana.410120240 | PMID = 7125611 }}</ref> | ||
**Can be seen in newborn -> due to increased bilirubin levels. | |||
**Best seen when looking from top through the tube. <ref name="pmid3981778">{{Cite journal | last1 = Bremer | first1 = HL. | title = Identification of xanthochromia. | journal = JAMA | volume = 253 | issue = 17 | pages = 2496 | month = May | year = 1985 | doi = | PMID = 3981778 }}</ref> | |||
**pink (free hemoglobin directly after bleeding) to yellow (bilirubin after one day). | |||
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File:Gram Stain Anthrax.jpg | Gram-positive Anthrax bacteria in a CSF specimen (WC/TenOfAllTrades). | File:Gram Stain Anthrax.jpg | Gram-positive Anthrax bacteria in a CSF specimen (WC/TenOfAllTrades). | ||
</gallery> | </gallery> | ||
DDx: | |||
*[[TBC]] | |||
*Fungal meningitis | |||
==Viral meningitis== | ==Viral meningitis== | ||