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Difference between revisions of "Renal oncocytoma"
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*[[CD117]] +ve.<ref>{{Cite journal | last1 = Krüger | first1 = S. | last2 = Sotlar | first2 = K. | last3 = Kausch | first3 = I. | last4 = Horny | first4 = HP. | title = Expression of KIT (CD117) in renal cell carcinoma and renal oncocytoma. | journal = Oncology | volume = 68 | issue = 2-3 | pages = 269-75 | month = | year = 2005 | doi = 10.1159/000086783 | PMID = 16015044 }}</ref> | *[[CD117]] +ve.<ref>{{Cite journal | last1 = Krüger | first1 = S. | last2 = Sotlar | first2 = K. | last3 = Kausch | first3 = I. | last4 = Horny | first4 = HP. | title = Expression of KIT (CD117) in renal cell carcinoma and renal oncocytoma. | journal = Oncology | volume = 68 | issue = 2-3 | pages = 269-75 | month = | year = 2005 | doi = 10.1159/000086783 | PMID = 16015044 }}</ref> | ||
**ChRCC also +ve. | **ChRCC also +ve. | ||
*GATA-3 -ve. | *GATA-3 usually -ve (38 cases negative of 47 cases).<ref name=pmid2431520>{{cite journal |authors=Gonzalez-Roibon N, Faraj SF, Munari E, Bezerra SM, Albadine R, Sharma R, Argani P, Allaf ME, Netto GJ |title=Comprehensive profile of GATA binding protein 3 immunohistochemical expression in primary and metastatic renal neoplasms |journal=Hum Pathol |volume=45 |issue=2 |pages=244–8 |date=February 2014 |pmid=24315206 |doi=10.1016/j.humpath.2013.08.020 |url=}}</ref> | ||
**+ve in [[low-grade oncocytic renal tumour]]. | **+ve in [[low-grade oncocytic renal tumour]]. | ||
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A panel: | A panel: | ||
*CK7, PAX8, CD117, CD10, [[Mueller-Mowry stain]], GATA-3. | *CK7, PAX8, CD117, CD10, [[Mueller-Mowry stain]], GATA-3. | ||
===Comparison between some renal tumours with eosinophilic cytoplasm=== | |||
{| class="wikitable sortable" | |||
!Tumour | |||
![[CK7]] | |||
![[CD117]] | |||
![[GATA3]] | |||
|- | |||
| Renal oncocytoma | |||
| -ve † | |||
| +ve | |||
| -ve/+ve | |||
|- | |||
| [[Chromophobe renal cell carcinoma]] | |||
| +ve ‡ | |||
| +ve | |||
| -ve | |||
|- | |||
| [[Low-grade oncocytic tumour]] | |||
| +ve | |||
| -ve | |||
| +ve | |||
|- | |||
|} | |||
† may have scattered positive cells<br> | |||
‡ diffuse and strong | |||
==Sign out== | ==Sign out== | ||