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Difference between revisions of "Starvation"
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'''Starvation''' is defined as deprivation of food for a lengthy period. Generally, it is due to lack of food, inability to eat or lack of desire to eat. It may | '''Starvation''' is defined as deprivation of food for a lengthy period. Generally, it is due to lack of food, inability to eat or lack of desire to eat. It may include people that can eat but cannot absorb the nutrients in their food. | ||
This article covers ''[[serous fat atrophy]]'' as it is classically seen in starvation. | This article covers ''[[serous fat atrophy]]'' as it is classically seen in starvation. | ||
''Cachexia'' and ''dystrophic mesenteric adipocytes'' direct here. | |||
=Starvation= | =Starvation= | ||
===Causes of starvation=== | ===Causes of starvation=== | ||
*Psychiatric: | *Psychiatric: | ||
**Dementia. | **[[Dementia]]. | ||
**Anorexia nervosa. | **Anorexia nervosa. | ||
**Disorder with delusions, e.g. schizophrenia, bipolar affective disorder - belief one is being poisoned. | **Disorder with delusions, e.g. schizophrenia, bipolar affective disorder - belief one is being poisoned. | ||
| Line 50: | Line 52: | ||
DDx: | DDx: | ||
*[[Signet ring cell carcinoma]].<ref name=pmid6222282>{{Cite journal | last1 = Clarke | first1 = BE. | last2 = Brown | first2 = DJ. | last3 = Xipell | first3 = JM. | title = Gelatinous transformation of the bone marrow. | journal = Pathology | volume = 15 | issue = 1 | pages = 85-8 | month = Jan | year = 1983 | doi = | PMID = 6222282 }}</ref> | *[[Signet ring cell carcinoma]].<ref name=pmid6222282>{{Cite journal | last1 = Clarke | first1 = BE. | last2 = Brown | first2 = DJ. | last3 = Xipell | first3 = JM. | title = Gelatinous transformation of the bone marrow. | journal = Pathology | volume = 15 | issue = 1 | pages = 85-8 | month = Jan | year = 1983 | doi = | PMID = 6222282 }}</ref> | ||
*[[Liposarcoma]]. | |||
*[[Malignant mesothelioma]]. | |||
*[[Vascular lesions]]. | |||
====Images==== | ====Images==== | ||
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Image:Fat_atrophy_-_very_high_mag.jpg | Serous fat atrophy - very high mag. (WC) | Image:Fat_atrophy_-_very_high_mag.jpg | Serous fat atrophy - very high mag. (WC) | ||
</gallery> | </gallery> | ||
===IHC=== | |||
Features:<ref>{{cite journal |authors=van Haeringen B, Francis L, Olive E, James D |title=Adipocyte Atrophy Mimicking Signet Ring Cell Carcinoma of the Gallbladder |journal=Case Rep Pathol |volume=2021 |issue= |pages=4676885 |date=2021 |pmid=34754523 |pmc=8572618 |doi=10.1155/2021/4676885 |url=}}</ref> | |||
*S-100 +ve (key stain). | |||
*AE1/AE3 -ve (key stain). | |||
*CD68 -ve. | |||
=See also= | =See also= | ||
*[[Autopsy]]. | *[[Autopsy]]. | ||
*[[Signet ring cell carcinoma]]. | |||
=References= | =References= | ||