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Difference between revisions of "Squamous cell carcinoma of the head and neck"
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Squamous cell carcinoma of the head and neck (view source)
Revision as of 18:09, 5 March 2024
, 5 Marchno edit summary
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| Micro = | | Micro = | ||
| Subtypes = keratinizing type, undifferentiated type, nonkeratinizing type | | Subtypes = keratinizing type, undifferentiated type, nonkeratinizing type | ||
| LMDDx = [[squamous dysplasia of the head and neck]], [[HPV-associated head and neck squamous cell carcinoma]], [[nasopharyngeal carcinoma]], [[malignant melanoma]], metastatic [[squamous cell carcinoma]], [[NUT carcinoma]] | | LMDDx = [[squamous dysplasia of the head and neck]], [[HPV-associated head and neck squamous cell carcinoma]], [[nasopharyngeal carcinoma]], [[malignant melanoma]], metastatic [[squamous cell carcinoma]] (esp. [[skin SCC]] of lateral head), [[NUT carcinoma]], [[pseudoepitheliomatous hyperplasia]] | ||
| Stains = | | Stains = | ||
| IHC = p63 +ve, CK5/6, p16 -ve, EBER -ve | | IHC = p63 +ve, CK5/6, p16 -ve, EBER -ve | ||
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*[[NUT carcinoma]] - has well-differentiated squamous "islands" that are sharply demarcated from poorly differentiated surrounding tumour. | *[[NUT carcinoma]] - has well-differentiated squamous "islands" that are sharply demarcated from poorly differentiated surrounding tumour. | ||
*[[Neuroendocrine tumour]]. | *[[Neuroendocrine tumour]]. | ||
*Metastatic [[skin SCC|squamous cell carcinoma of skin]] - esp. parotid lesions | *Metastatic [[skin SCC|squamous cell carcinoma of skin]] - esp. parotid lesions, history of skin SCC (esp. lateral aspect of head).<ref name=pmid16783833>{{cite journal |authors=Vauterin TJ, Veness MJ, Morgan GJ, Poulsen MG, O'Brien CJ |title=Patterns of lymph node spread of cutaneous squamous cell carcinoma of the head and neck |journal=Head Neck |volume=28 |issue=9 |pages=785–91 |date=September 2006 |pmid=16783833 |doi=10.1002/hed.20417 |url=}}</ref> | ||
*[[Pseudoepitheliomatous hyperplasia]]. | |||
====Invasion==== | ====Invasion==== | ||