Difference between revisions of "Vocal cord nodule"
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'''Vocal cord nodule''', also '''vocal cord polyp''' and '''singer's nodule''', is a benign pathology of the [[head and neck pathology|head and neck]]. | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Laryngeal_nodule_(1).jpg | |||
| Width = | |||
| Caption = Laryngeal nodule | |||
| Synonyms = singer's nodule, vocal fold nodule | |||
| Micro = early: edema, fibroblasts proliferation; late: subepithelial hyaline / stromal hyaline, blood vessels - dilated | |||
| Subtypes = | |||
| LMDDx = [[amyloidosis]], [[granular cell tumour]], spindle cell [[squamous cell carcinoma of the head and neck|squamous cell carcinoma]], myxoma, ductal-type cyst | |||
| Stains = [[congo red stain|congo red]] -ve | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[vocal cord]] - also see ''[[head and neck pathology]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = +/-hoarseness | |||
| Symptoms = | |||
| Prevalence = common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Vocal cord nodule''', also '''vocal cord polyp''', '''vocal fold nodule''' and '''singer's nodule''', is a benign pathology of the [[head and neck pathology|head and neck]]. | |||
==General== | ==General== | ||
*Benign. | *Benign. | ||
*Etiology: overuse, "phonatory trauma"<ref name=pmid19730264>{{Cite journal | last1 = Karkos | first1 = PD. | last2 = McCormick | first2 = M. | title = The etiology of vocal fold nodules in adults. | journal = Curr Opin Otolaryngol Head Neck Surg | volume = 17 | issue = 6 | pages = 420-3 | month = Dec | year = 2009 | doi = 10.1097/MOO.0b013e328331a7f8 | PMID = 19730264 }}</ref> (yelling). | |||
*Etiology: overuse, | |||
Clinical: | |||
*Hoarseness.<ref name=pmid7502253>{{Cite journal | last1 = Müller | first1 = R. | title = [Hoarseness]. | journal = Ther Umsch | volume = 52 | issue = 11 | pages = 759-62 | month = Nov | year = 1995 | doi = | PMID = 7502253 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
| Line 21: | Line 54: | ||
*[[Amyloidosis]]. | *[[Amyloidosis]]. | ||
*[[Granular cell tumour]]. | *[[Granular cell tumour]]. | ||
*Spindle cell [[squamous cell carcinoma of the head and neck|squamous cell carcinoma]]. | *Spindle cell [[squamous cell carcinoma of the head and neck|squamous cell carcinoma]].<ref>{{Cite journal | last1 = Soylu | first1 = L. | last2 = Aydogan | first2 = B. | last3 = Tunali | first3 = N. | last4 = Ozsahinoglu | first4 = C. | title = Report of a rare case of vocal fold carcinoma that was obscured by a prominent vocal fold polyp. | journal = Ear Nose Throat J | volume = 78 | issue = 8 | pages = 601-2 | month = Aug | year = 1999 | doi = | PMID = 10485155 }}</ref> | ||
*Myxoma. | *Myxoma. | ||
*Ductal-type cyst. | *Ductal-type cyst. | ||
*[[Rheumatoid nodule]].<ref>{{Cite journal | last1 = Abdou | first1 = AG. | last2 = Asaad | first2 = NY. | title = Rheumatoid nodule of the vocal cord. | journal = Int J Surg Pathol | volume = 20 | issue = 5 | pages = 481-2 | month = Oct | year = 2012 | doi = 10.1177/1066896912448426 | PMID = 22674917 }}</ref> | *[[Rheumatoid nodule]].<ref name=pmid22674917>{{Cite journal | last1 = Abdou | first1 = AG. | last2 = Asaad | first2 = NY. | title = Rheumatoid nodule of the vocal cord. | journal = Int J Surg Pathol | volume = 20 | issue = 5 | pages = 481-2 | month = Oct | year = 2012 | doi = 10.1177/1066896912448426 | PMID = 22674917 }}</ref> | ||
===Images=== | ===Images=== | ||
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==Sign out== | ==Sign out== | ||
<pre> | |||
Left Vocal Cord Polyp, Excision: | |||
- Stratified squamous epithelium with compact hyperkeratosis and stromal | |||
edema, consistent with benign vocal cord nodule or polyp. | |||
- NEGATIVE for malignancy. | |||
</pre> | |||
===Block letters=== | |||
<pre> | <pre> | ||
VOCAL CORD LESION, EXCISION: | VOCAL CORD LESION, EXCISION: | ||
- STRATIFIED SQUAMOUS EPITHELIUM WITH PARAKERATOSIS AND | - STRATIFIED SQUAMOUS EPITHELIUM WITH PARAKERATOSIS AND STROMAL EDEMA, CONSISTENT | ||
WITH BENIGN VOCAL CORD NODULE OR POLYP. | WITH BENIGN VOCAL CORD NODULE OR POLYP. | ||
- NEGATIVE FOR MALIGNANCY. | - NEGATIVE FOR MALIGNANCY. | ||
Latest revision as of 18:27, 11 December 2023
| Vocal cord nodule | |
|---|---|
| Diagnosis in short | |
.jpg) Laryngeal nodule | |
|
| |
| Synonyms | singer's nodule, vocal fold nodule |
|
| |
| LM | early: edema, fibroblasts proliferation; late: subepithelial hyaline / stromal hyaline, blood vessels - dilated |
| LM DDx | amyloidosis, granular cell tumour, spindle cell squamous cell carcinoma, myxoma, ductal-type cyst |
| Stains | congo red -ve |
| Site | vocal cord - also see head and neck pathology |
|
| |
| Signs | +/-hoarseness |
| Prevalence | common |
| Prognosis | benign |
Vocal cord nodule, also vocal cord polyp, vocal fold nodule and singer's nodule, is a benign pathology of the head and neck.
General
- Benign.
- Etiology: overuse, "phonatory trauma"[1] (yelling).
Clinical:
- Hoarseness.[2]
Microscopic
Features:[3]
- Early:
- Edema.
- Fibroblasts proliferation.
- Late:
- Subepithelial hyaline / stromal hyaline.
- Blood vessels - dilated.
Notes:
- No inflammation.
DDx:[4]
- Amyloidosis.
- Granular cell tumour.
- Spindle cell squamous cell carcinoma.[5]
- Myxoma.
- Ductal-type cyst.
- Rheumatoid nodule.[6]
Images
Laryngeal nodule - low mag. (WC)
Laryngeal nodule (WC)
.jpg)
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Left Vocal Cord Polyp, Excision: - Stratified squamous epithelium with compact hyperkeratosis and stromal edema, consistent with benign vocal cord nodule or polyp. - NEGATIVE for malignancy.
Block letters
VOCAL CORD LESION, EXCISION: - STRATIFIED SQUAMOUS EPITHELIUM WITH PARAKERATOSIS AND STROMAL EDEMA, CONSISTENT WITH BENIGN VOCAL CORD NODULE OR POLYP. - NEGATIVE FOR MALIGNANCY.
VOCAL CORD LESION, EXCISION: - STRATIFIED SQUAMOUS EPITHELIUM WITH PARAKERATOSIS AND SUBEPITHELIAL HYALINE MATERIAL, CONSISTENT WITH WITH VOCAL CORD NODULE OR POLYP. - NEGATIVE FOR MALIGNANCY.
See also
References
- ↑ Karkos, PD.; McCormick, M. (Dec 2009). "The etiology of vocal fold nodules in adults.". Curr Opin Otolaryngol Head Neck Surg 17 (6): 420-3. doi:10.1097/MOO.0b013e328331a7f8. PMID 19730264.
- ↑ Müller, R. (Nov 1995). "[Hoarseness].". Ther Umsch 52 (11): 759-62. PMID 7502253.
- ↑ URL: http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970310-2. Accessed on: 4 February 2011.
- ↑ Thompson, Lester D. R. (2006). Head and Neck Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 9. ISBN 978-0443069604.
- ↑ Soylu, L.; Aydogan, B.; Tunali, N.; Ozsahinoglu, C. (Aug 1999). "Report of a rare case of vocal fold carcinoma that was obscured by a prominent vocal fold polyp.". Ear Nose Throat J 78 (8): 601-2. PMID 10485155.
- ↑ Abdou, AG.; Asaad, NY. (Oct 2012). "Rheumatoid nodule of the vocal cord.". Int J Surg Pathol 20 (5): 481-2. doi:10.1177/1066896912448426. PMID 22674917.