Pleomorphic adenoma: Difference between revisions
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'''Pleomorphic adenoma''', abbreviated '''PA''', is a very common benign [[salivary gland]] tumour. | '''Pleomorphic adenoma''', abbreviated '''PA''', is a very common benign [[salivary gland]] tumour. | ||
It is also known as '''benign mixed tumour'''.<ref>URL: [http://radiopaedia.org/articles/pleomorphic-adenoma-of-the-salivary-glands http://radiopaedia.org/articles/pleomorphic-adenoma-of-the-salivary-glands]. Accessed on: 30 March 2016.</ref> | It is also known as '''benign mixed tumour'''.<ref>URL: [http://radiopaedia.org/articles/pleomorphic-adenoma-of-the-salivary-glands http://radiopaedia.org/articles/pleomorphic-adenoma-of-the-salivary-glands]. Accessed on: 30 March 2016.</ref><ref name=pmid19926180>{{Cite journal | last1 = Lingam | first1 = RK. | last2 = Daghir | first2 = AA. | last3 = Nigar | first3 = E. | last4 = Abbas | first4 = SA. | last5 = Kumar | first5 = M. | title = Pleomorphic adenoma (benign mixed tumour) of the salivary glands: its diverse clinical, radiological, and histopathological presentation. | journal = Br J Oral Maxillofac Surg | volume = 49 | issue = 1 | pages = 14-20 | month = Jan | year = 2011 | doi = 10.1016/j.bjoms.2009.09.014 | PMID = 19926180 }}</ref> | ||
==General== | ==General== | ||
Features: | Features: | ||
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not identified. Mitotic activity is not apparent. Unremarkable parotid gland and a | not identified. Mitotic activity is not apparent. Unremarkable parotid gland and a | ||
morphologically benign lymph node are present. Ink is seen on the tumour. | morphologically benign lymph node are present. Ink is seen on the tumour. | ||
====Biopsy==== | |||
The sections show a lesion with spindled (myoepithelial) cells and an epithelial component, on a background of a chondromyxoid stroma. No nuclear atypia is apparent. Mitotic activity is not identified. | |||
<pre> | |||
The tumour stains as follows: | |||
POSITIVE: CK7, S-100, SMA, GFAP (patchy). | |||
NEGATIVE: (none). | |||
PROLIFERATION (Ki-67): <2%. | |||
</pre> | |||
==See also== | ==See also== | ||