Difference between revisions of "Interval appendectomy"

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==General==
==General==
*Done to exclude neoplasm and recurrent appendicitis.<ref name=pmid31175422>{{cite journal |authors=de Jonge J, Bolmers MDM, Musters GD, van Rossem CC, Bemelman WA, van Geloven AAW |title=Predictors for interval appendectomy in non-operatively treated complicated appendicitis |journal=Int J Colorectal Dis |volume=34 |issue=7 |pages=1325–1332 |date=July 2019 |pmid=31175422 |doi=10.1007/s00384-019-03303-4 |url=}}</ref>
*Done to exclude neoplasm and recurrent appendicitis.<ref name=pmid31175422>{{cite journal |authors=de Jonge J, Bolmers MDM, Musters GD, van Rossem CC, Bemelman WA, van Geloven AAW |title=Predictors for interval appendectomy in non-operatively treated complicated appendicitis |journal=Int J Colorectal Dis |volume=34 |issue=7 |pages=1325–1332 |date=July 2019 |pmid=31175422 |doi=10.1007/s00384-019-03303-4 |url=}}</ref>
*Histologically may mimic Crohn's disease.<ref name=pmid12883248>{{cite journal |authors=Guo G, Greenson JK |title=Histopathology of interval (delayed) appendectomy specimens: strong association with granulomatous and xanthogranulomatous appendicitis |journal=Am J Surg Pathol |volume=27 |issue=8 |pages=1147–51 |date=August 2003 |pmid=12883248 |doi=10.1097/00000478-200308000-00013 |url=}}</ref>
*Histologically may mimic Crohn's disease.<ref name=pmid12883248>{{cite journal |authors=Guo G, Greenson JK |title=Histopathology of interval (delayed) appendectomy specimens: strong association with granulomatous and xanthogranulomatous appendicitis |journal=Am J Surg Pathol |volume=27 |issue=8 |pages=1147–51 |date=August 2003 |pmid=12883248 |doi=10.1097/00000478-200308000-00013 |url=}}</ref><ref name=pmid35076982>{{cite journal |authors=Malvar G, Peric M, Gonzalez RS |title=Interval appendicitis shows histological differences from acute appendicitis and may mimic Crohn disease and other forms of granulomatous appendicitis |journal=Histopathology |volume=80 |issue=6 |pages=965–973 |date=May 2022 |pmid=35076982 |doi=10.1111/his.14621 |url=}}</ref>


==Microscopic==
==Microscopic==
Features:
Features:<ref name=pmid35076982/>
*Muscularis propria eosinophils and/or [[plasma cell]]s.
*Muscularis propria eosinophils and/or [[plasma cell]]s.
*+/-Fibrosis.
*+/-Neutrophils in muscularis propria.
*+/-Muscularis propria [[neutrophil]]s.
*+/-Muscularis propria [[neutrophil]]s.
*+/-Granulatous inflammation.
*+/-Granulatous or xanthogranulomatous inflammation.


DDx:
DDx:
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<pre>
<pre>
Vermiform Appendix, Appendectomy:
Vermiform Appendix, Appendectomy:
- Benign appendix with mild mixed muscularis inflammation (plasma cells, eosinophils, possible rare neutrophils), see comment.
- Benign appendix with mild mixed muscularis inflammation (plasma cells, eosinophils), see comment.
    - NEGATIVE for acute appendicitis.


Comment:
Comment:
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==References==
==References==
{{Reflist|1}}
{{Reflist|2}}


[[Category:Gastrointestinal pathology]]
[[Category:Gastrointestinal pathology]]
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