Difference between revisions of "Fibromatoses"

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'''Fibromatoses''' are a group of benign stromal lesions that may be seen in [[pediatric pathology]] and may or may not be associated with [[syndromes]].
[[Image:Palmar fibromatosis - alt -- high mag.jpg|thumb|right|Micrograph showing a [[palmar fibromatosis]]. [[H&E stain]].]]
'''Fibromatoses''' are a group of benign stromal lesions that may or may not be associated with [[syndromes]].
 
''Plantar fibromatosis'' redirects here.


==Syndromes associated with fibromatoses==
==Syndromes associated with fibromatoses==
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===Superficial===
===Superficial===
*Palmar ([[Dupuytren's contracture]]).
*Palmar ([[Dupuytren's contracture]]).
*Plantar.  
*Plantar (Ledderhose disease<ref>{{cite journal |authors=Mozena JD, Hansen EK, Jones PC |title=Radiotherapy for Plantar Fibromas (Ledderhose Disease) |journal=J Am Podiatr Med Assoc |volume=112 |issue=1 |pages= |date=March 2022 |pmid=35324461 |doi=10.7547/19-008 |url=}}</ref><ref name=pmid35274715>{{cite journal |authors=Schoenfeld JD, Agaram NP, Lefkowitz RA, Kelly CM, Healey JH, Gounder MM |title=Sorafenib in Dupuytren and Ledderhose Disease |journal=Oncologist |volume=27 |issue=3 |pages=e294–e296 |date=March 2022 |pmid=35274715 |pmc=8914480 |doi=10.1093/oncolo/oyab050 |url=}}</ref>).
*Penile ([[Peyronie's disease]]).
*Penile ([[Peyronie's disease]]).


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*Beta-catenin +ve -- nuclear stain.
*Beta-catenin +ve -- nuclear stain.
*CD117 -ve.
*CD117 -ve.
*CD34 -ve.<ref name=pmid25349618>{{Cite journal  | last1 = Li Destri | first1 = G. | last2 = Ferraro | first2 = MJ. | last3 = Calabrini | first3 = M. | last4 = Pennisi | first4 = M. | last5 = Magro | first5 = G. | title = Desmoid-type fibromatosis of the mesentery: report of a sporadic case with emphasis on differential diagnostic problems. | journal = Case Rep Med | volume = 2014 | issue =  | pages = 850180 | month =  | year = 2014 | doi = 10.1155/2014/850180 | PMID = 25349618 }}</ref>


Image:
Image:
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==Sign out==
==Sign out==
===Deep===
<pre>
<pre>
SOFT TISSUE LESION, LEFT SHOULDER, CORE BIOPSY:
SOFT TISSUE LESION, LEFT SHOULDER, CORE BIOPSY:
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Positive: vimentin, SMA (rare), beta-catenin.
Positive: vimentin, SMA (rare), beta-catenin.
Negative: pankeratin, S-100, desmin, CD34 (stains vessels).
Negative: pankeratin, S-100, desmin, CD34 (stains vessels).
</pre>
===Plantar===
<pre>
Left Foot, Plantar Fascia, Fasciectomy:
- Plantar fibromatosis.
</pre>
</pre>


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[[Category:Weird stuff]]
[[Category:Weird stuff]]
[[Category:Soft tissue pathology]]
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