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'''Fibromatoses''' are a group of benign stromal lesions that | [[Image:Palmar fibromatosis - alt -- high mag.jpg|thumb|right|Micrograph showing a [[palmar fibromatosis]]. [[H&E stain]].]] | ||
'''Fibromatoses''' are a group of benign stromal lesions that may or may not be associated with [[syndromes]]. | |||
''Plantar fibromatosis'' redirects here. | |||
==Syndromes associated with fibromatoses== | ==Syndromes associated with fibromatoses== | ||
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===Superficial=== | ===Superficial=== | ||
*Palmar ([[Dupuytren's contracture]]). | *Palmar ([[Dupuytren's contracture]]). | ||
*Plantar. | *Plantar (Ledderhose disease<ref>{{cite journal |authors=Mozena JD, Hansen EK, Jones PC |title=Radiotherapy for Plantar Fibromas (Ledderhose Disease) |journal=J Am Podiatr Med Assoc |volume=112 |issue=1 |pages= |date=March 2022 |pmid=35324461 |doi=10.7547/19-008 |url=}}</ref><ref name=pmid35274715>{{cite journal |authors=Schoenfeld JD, Agaram NP, Lefkowitz RA, Kelly CM, Healey JH, Gounder MM |title=Sorafenib in Dupuytren and Ledderhose Disease |journal=Oncologist |volume=27 |issue=3 |pages=e294–e296 |date=March 2022 |pmid=35274715 |pmc=8914480 |doi=10.1093/oncolo/oyab050 |url=}}</ref>). | ||
*Penile ([[Peyronie's disease]]). | *Penile ([[Peyronie's disease]]). | ||
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*Beta-catenin +ve -- nuclear stain. | *Beta-catenin +ve -- nuclear stain. | ||
*CD117 -ve. | *CD117 -ve. | ||
*CD34 -ve.<ref name=pmid25349618>{{Cite journal | last1 = Li Destri | first1 = G. | last2 = Ferraro | first2 = MJ. | last3 = Calabrini | first3 = M. | last4 = Pennisi | first4 = M. | last5 = Magro | first5 = G. | title = Desmoid-type fibromatosis of the mesentery: report of a sporadic case with emphasis on differential diagnostic problems. | journal = Case Rep Med | volume = 2014 | issue = | pages = 850180 | month = | year = 2014 | doi = 10.1155/2014/850180 | PMID = 25349618 }}</ref> | |||
Image: | Image: | ||
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==Sign out== | ==Sign out== | ||
===Deep=== | |||
<pre> | <pre> | ||
SOFT TISSUE LESION, LEFT SHOULDER, CORE BIOPSY: | SOFT TISSUE LESION, LEFT SHOULDER, CORE BIOPSY: | ||
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Positive: vimentin, SMA (rare), beta-catenin. | Positive: vimentin, SMA (rare), beta-catenin. | ||
Negative: pankeratin, S-100, desmin, CD34 (stains vessels). | Negative: pankeratin, S-100, desmin, CD34 (stains vessels). | ||
</pre> | |||
===Plantar=== | |||
<pre> | |||
Left Foot, Plantar Fascia, Fasciectomy: | |||
- Plantar fibromatosis. | |||
</pre> | </pre> | ||
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[[Category:Weird stuff]] | [[Category:Weird stuff]] | ||
[[Category:Soft tissue pathology]] | |||
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