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Difference between revisions of "Palmar fibromatosis"
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| Caption = Palmar fibromatosis. [[H&E stain]]. | | Caption = Palmar fibromatosis. [[H&E stain]]. | ||
| Micro = poorly demarcated, usu. multiple lesions/multiple nodules, composed of bland spindle cells in dense collagen; spindle cells have pale grey cytoplasm and a pale ovoid | | Micro = poorly demarcated, usu. multiple lesions/multiple nodules, composed of bland spindle cells in dense collagen; spindle cells have pale grey cytoplasm and a pale ovoid nucleus with small round nucleolus, +/-giant cells (rare) | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[calcifying aponeurotic fibroma]], extra-abdominal desmoid [[fibromatosis]], inclusion body [[fibromatosis]], [[fibrosarcoma]], [[synovial sarcoma]], [[epithelioid sarcoma]], [[metastasis|metastatic]] [[metaplastic carcinoma]] | | LMDDx = [[calcifying aponeurotic fibroma]], extra-abdominal desmoid [[fibromatosis]], inclusion body [[fibromatosis]], [[fibrosarcoma]], [[synovial sarcoma]], [[epithelioid sarcoma]], [[metastasis|metastatic]] [[metaplastic carcinoma]] | ||
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The bigger topic of fibromatoses is covered in the article ''[[fibromatosis]]''. | The bigger topic of fibromatoses is covered in the article ''[[fibromatosis]]''. | ||
''Palmar fascia'' directs to this article. | |||
==General== | ==General== | ||
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*Extra-abdominal desmoid [[fibromatosis]] - extremely rare on hands and feet, muscle infiltrative. | *Extra-abdominal desmoid [[fibromatosis]] - extremely rare on hands and feet, muscle infiltrative. | ||
*Inclusion body [[fibromatosis]]. | *Inclusion body [[fibromatosis]]. | ||
*[[Fibrosarcoma]] - atypia, necrosis, herring | *[[Fibrosarcoma]] - atypia, necrosis, [[herring bone pattern]]. | ||
*[[Synovial sarcoma]] - one mass. | *[[Synovial sarcoma]] - one mass. | ||
*[[Epithelioid sarcoma]] - necrosis, atypia. | *[[Epithelioid sarcoma]] - necrosis, atypia. | ||
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Image: Palmar fibromatosis -- very high mag.jpg | PF - very high mag. | Image: Palmar fibromatosis -- very high mag.jpg | PF - very high mag. | ||
</gallery> | </gallery> | ||
www | <gallery> | ||
Image:WVSOM_Pacinian_Corpuscle.JPG | Pacinian corpuscle. (WC) | |||
Image:Tendon_-_intermed_mag.jpg | Tendon without fibromatosis - intermed. mag. (WC) | |||
</gallery> | |||
====www==== | |||
*[http://www.biomedsearch.com/attachments/display/00/16/69/68/16696857/1479-5876-4-21-2.jpg Palmer fibromatosis (biomedsearch.com)].<ref name=pmid16696857>{{cite journal |author=Wang L, Zhu H |title=Clonal analysis of palmar fibromatosis: a study whether palmar fibromatosis is a real tumor |journal=J Transl Med |volume=4 |issue= |pages=21 |year=2006 |pmid=16696857 |pmc=1488873 |doi=10.1186/1479-5876-4-21 |url=http://www.biomedsearch.com/nih/Clonal-analysis-palmar-fibromatosis-study/16696857.html}}</ref> | *[http://www.biomedsearch.com/attachments/display/00/16/69/68/16696857/1479-5876-4-21-2.jpg Palmer fibromatosis (biomedsearch.com)].<ref name=pmid16696857>{{cite journal |author=Wang L, Zhu H |title=Clonal analysis of palmar fibromatosis: a study whether palmar fibromatosis is a real tumor |journal=J Transl Med |volume=4 |issue= |pages=21 |year=2006 |pmid=16696857 |pmc=1488873 |doi=10.1186/1479-5876-4-21 |url=http://www.biomedsearch.com/nih/Clonal-analysis-palmar-fibromatosis-study/16696857.html}}</ref> | ||
*[http://alf3.urz.unibas.ch/pathopic/e/getpic-fra.cfm?id=8235 Palmar fibromatosis (unibas.ch)]. | *[http://alf3.urz.unibas.ch/pathopic/e/getpic-fra.cfm?id=8235 Palmar fibromatosis (unibas.ch)]. | ||
==IHC== | ==IHC== | ||
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==Sign out== | ==Sign out== | ||
===Left=== | ===Left=== | ||
<pre> | |||
Palmar Fascia, Left Ring Finger, Fasciectomy: | |||
- Palmar fibromatosis. | |||
</pre> | |||
<pre> | |||
Palmar Fascia, Left Long Finger, Fasciectomy: | |||
- Palmar fibromatosis (Dupuytren's contracture). | |||
</pre> | |||
====Block letters==== | |||
<pre> | <pre> | ||
PALMAR FASCIA, LEFT, FASCIECTOMY: | PALMAR FASCIA, LEFT, FASCIECTOMY: | ||
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===Missed fibromatosis=== | ===Missed fibromatosis=== | ||
<pre> | |||
Palmar Fascia, Left Hand, Fasciectomy: | |||
- Palmar fascia within normal limits and benign fibroadipose tissue - in an | |||
individual with a preoperative diagnosis of palmar fibromatosis. | |||
- NEGATIVE for malignancy. | |||
Comment: | |||
A beta-catenin is NEGATIVE. Deepers were cut (x6); they are noncontributory. | |||
</pre> | |||
=====Alternate===== | |||
<pre> | |||
Palmar Fascia, Left, Fasciectomy: | |||
- Palmar fascia within normal limits and benign fibroadipose tissue - in an | |||
individual with a clinical history of palmar fibromatosis. | |||
- NEGATIVE for malignancy. | |||
</pre> | |||
=====History not provided===== | |||
<pre> | |||
Palmar Fascia, Left, Fasciectomy: | |||
- Palmar fascia within normal limits and benign fibroadipose tissue, in an | |||
individual clinically described as having palmar fibromatosis. | |||
- NEGATIVE for malignancy. | |||
</pre> | |||
====Block letters==== | |||
<pre> | <pre> | ||
PALMAR FASCIA, LEFT, FASCIECTOMY: | PALMAR FASCIA, LEFT, FASCIECTOMY: | ||