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Difference between revisions of "Lymphoepithelioma-like carcinoma of the urinary bladder"
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Lymphoepithelioma-like carcinoma of the urinary bladder (view source)
Revision as of 14:50, 4 August 2022
, 14:50, 4 August 2022no edit summary
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| Synonyms = | | Synonyms = | ||
| Micro = squamoid cells with abundant dense cytoplasm central nuclei +/- small/indistinct nucleoli, prominent lymphoid infiltrate | | Micro = squamoid cells with abundant dense cytoplasm central nuclei +/- small/indistinct nucleoli, prominent lymphoid infiltrate | ||
| Subtypes = subtype of [[urothelial carcinoma]] | | Subtypes = (subtype of [[urothelial carcinoma]]) | ||
| LMDDx = [[lymphoma]], [[urothelial carcinoma]] and inflammation, metastatic [[lymphoepithelioma-like carcinoma]] | | LMDDx = [[lymphoma]], [[urothelial carcinoma]] and inflammation, metastatic [[lymphoepithelioma-like carcinoma]] | ||
| Stains = | | Stains = | ||
| IHC = CK34betaE12 +ve, p63 +ve/-ve, CK7 +ve/-ve, CK20 -ve, CD30 -ve | | IHC = [[CK34betaE12]] +ve, p63 +ve/-ve, [[CK7]] +ve/-ve, [[CK20]] -ve, CD30 -ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
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*Prominent lymphoid infiltrate - '''key feature'''. | *Prominent lymphoid infiltrate - '''key feature'''. | ||
*+/-[[Urothelial carcinoma in situ]]. | *+/-[[Urothelial carcinoma in situ]]. | ||
Note: | |||
*Peritumoural lymphoid aggregates are typical.<ref name=pmid19847088>{{Cite journal | last1 = Singh | first1 = NG. | last2 = Mannan | first2 = AA. | last3 = Rifaat | first3 = AA. | last4 = Kahvic | first4 = M. | title = Lymphoepithelioma-like carcinoma of the urinary bladder: report of a rare case. | journal = Ann Saudi Med | volume = 29 | issue = 6 | pages = 478-81 | month = | year = | doi = 10.4103/0256-4947.57173 | PMID = 19847088 }}</ref> | |||
DDx: | DDx: | ||
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</gallery> | </gallery> | ||
www: | www: | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881438/figure/F0002/ LELC of the urinary bladder - low mag. (nih.gov)].<ref name=pmid19847088>{{Cite journal | last1 = Singh | first1 = NG. | last2 = Mannan | first2 = AA. | last3 = Rifaat | first3 = AA. | last4 = Kahvic | first4 = M. | title = Lymphoepithelioma-like carcinoma of the urinary bladder: report of a rare case. | journal = Ann Saudi Med | volume = 29 | issue = 6 | pages = 478-81 | month = | year = | doi = 10.4103/0256-4947.57173 | PMID = 19847088 }} | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881438/figure/F0002/ LELC of the urinary bladder - low mag. (nih.gov)].<ref name=pmid19847088>{{Cite journal | last1 = Singh | first1 = NG. | last2 = Mannan | first2 = AA. | last3 = Rifaat | first3 = AA. | last4 = Kahvic | first4 = M. | title = Lymphoepithelioma-like carcinoma of the urinary bladder: report of a rare case. | journal = Ann Saudi Med | volume = 29 | issue = 6 | pages = 478-81 | month = | year = | doi = 10.4103/0256-4947.57173 | PMID = 19847088 }}</ref> | ||
</ref> | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881438/figure/F0003/ LELC of the urinary bladder - high mag. (nih.gov)].<ref name=pmid19847088/> | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881438/figure/F0003/ LELC of the urinary bladder - high mag. (nih.gov)].<ref name=pmid19847088/> | ||