48,938
edits
Difference between revisions of "Prostate chips grossing"
Jump to navigation
Jump to search
→Formula: tweak
(→Formula: tweak) |
|||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
This article deals with '''prostate chips grossing'''. ''TURP specimens'' | This article deals with '''prostate chips grossing'''. ''TURP specimens'' and ''TURP grossing'' redirect here. | ||
==Introduction== | ==Introduction== | ||
Prostate chips are generated from ''transurethral resection of the prostate'' (TURP) procedures. These are generally for relieving urinary obstruction due to [[nodular hyperplasia of the prostate]] (benign prostatic hyperplasia); however, urinary obstruction may be secondary to [[prostate cancer]]. Thus, the job of the pathologist here, usually, is excluding an incidental [[cancer]]. | Prostate chips are generated from ''transurethral resection of the prostate'' (TURP) procedures. These are generally for relieving urinary obstruction due to [[nodular hyperplasia of the prostate]] (benign prostatic hyperplasia); however, urinary obstruction may be secondary to [[prostate cancer]]. Thus, the job of the pathologist here, usually, is excluding an incidental [[cancer]]. | ||
| Line 21: | Line 21: | ||
===Protocol notes=== | ===Protocol notes=== | ||
What to look for/feel for:<ref name=Ref_Lester398>{{Ref Lester|398}}</ref> | What to look for/feel for:<ref name=Ref_Lester398>{{Ref Lester|398}}</ref> | ||
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
| Line 52: | Line 36: | ||
|- | |- | ||
|} | |} | ||
====Sampling==== | |||
Number of cassettes:<ref name=Ref_Lester398>{{Ref Lester|398}}</ref> | |||
*<= 12 grams: [[EIT]]. | |||
*>12 grams: embed 12 grams ''and'' 1 cassette for every additional 5 grams. | |||
**If the prostate chips have a mass of: | |||
***16 grams: 6-8 cassettes for 12 grams + 1 cassette = 7-9 cassettes. | |||
***21 grams: 6-8 cassettes for 12 grams + 2 cassettes = 7-9 cassettes. | |||
Note: | |||
*If a minimal cancer is found in a partially submitted specimen, it is reasonable to stop there as submitting more tissue or the remainder is unlikely to change the [[prostate cancer grading|grade]] or extent of involvement.<ref name=pmid18684032>{{Cite journal | last1 = Trpkov | first1 = K. | last2 = Thompson | first2 = J. | last3 = Kulaga | first3 = A. | last4 = Yilmaz | first4 = A. | title = How much tissue sampling is required when unsuspected minimal prostate carcinoma is identified on transurethral resection? | journal = Arch Pathol Lab Med | volume = 132 | issue = 8 | pages = 1313-6 | month = Aug | year = 2008 | doi = 10.1043/1543-2165(2008)132[1313:HMTSIR]2.0.CO;2 | PMID = 18684032 }}</ref> | |||
=====Formula===== | |||
<math> | |||
N = (m -12)/5 + 8 | |||
</math> | |||
<br>Where: | |||
<br>N = number of blocks. | |||
<br>m = mass of the prostate tissue in grams. | |||
===Alternate approaches=== | ===Alternate approaches=== | ||