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Usual interstitial pneumonia (view source)
Revision as of 22:32, 7 February 2022
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Image:Fibroblast focus.jpg|UIP - fibroblast focus - high mag. (WC) | Image:Fibroblast focus.jpg|UIP - fibroblast focus - high mag. (WC) | ||
</gallery> | </gallery> | ||
==Sign out== | |||
<pre> | |||
A. Lung, Right Lower Lobe, Wedge Biopsy: | |||
- Usual interstitial pneumonia, see comment and microscopic. | |||
B. Lung, Right Middle Lobe, Wedge Biopsy: | |||
- Usual interstitial pneumonia, see comment and microscopic. | |||
C. Lung, Right Upper Lobe, Wedge Biopsy: | |||
- Usual interstitial pneumonia, see comment and microscopic. | |||
Comment: | |||
There are no findings to specifically suggest hypersensitivity. Clinical and radiologic | |||
correlation is suggested. | |||
</pre> | |||
===Alternate=== | |||
<pre> | |||
Right Lower Lobe of Lung, Wedge Resection: | |||
- Usual interstitial pneumonia (UIP) pattern (fibroblast foci, bronchiolization, | |||
extensive fibroelastotic scarring and focal calcification/bone formation), see comment. | |||
Comment: | |||
UIP pattern may be idiopathic. It is also be seen in the context of collagen vascular diseases, hypersensitivity reactions, and drugs; these need to be considered in clinical context along with the imaging findings. | |||
</pre> | |||
===Micro=== | |||
<pre> | |||
Sections show lung parenchyma with: | |||
Fibrosis (severity; lobar location): present (moderate-to-severe; peripheral predominant). | |||
Fibrosis - lung field predominance: lower lobe > middle lobe > upper lobe. | |||
Fibroblast foci: present. | |||
Temporal heterogeneity: present. | |||
Spatial heterogeneity: present. | |||
Peripheral cyst formation: present. | |||
Inflammation: present - patchy, lymphocyte predominant. | |||
Granulomatous inflammation: absent. | |||
Blood vessel changes: present, moderate-to-severe. | |||
Airspace changes: mucous plugs. | |||
</pre> | |||
==See also== | ==See also== | ||