Difference between revisions of "CD117"

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'''CD117''' is common [[immunostain]].  
'''CD117''' is common [[immunostain]].  
==Normal tissue positive==
*Mast cells.<ref name=pmid16082245>{{cite journal |authors=Miettinen M, Lasota J |title=KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation |journal=Appl Immunohistochem Mol Morphol |volume=13 |issue=3 |pages=205–20 |date=September 2005 |pmid=16082245 |doi=10.1097/01.pai.0000173054.83414.22 |url=}}</ref>
*Cajal cells.<ref name=pmid16082245/>
*Germ cells.<ref name=pmid16082245/>
*Melanocytes.<ref name=pmid16082245/>


==Positive==
==Positive==
*[[Gastrointestinal stromal tumour]].
*[[Gastrointestinal stromal tumour]].
*[[Seminoma]].
*[[Seminoma]].<ref name=pmid24832161>{{cite journal |author=Ulbright TM, Tickoo SK, Berney DM, Srigley JR |title=Best practices recommendations in the application of immunohistochemistry in testicular tumors: report from the international society of urological pathology consensus conference |journal=Am. J. Surg. Pathol. |volume=38 |issue=8 |pages=e50–9 |year=2014 |month=August |pmid=24832161 |doi=10.1097/PAS.0000000000000233 |url=}}</ref>
*[[Renal oncocytoma]].
*[[Renal oncocytoma]].
*[[Chromophobe renal cell carcinoma]].
*[[Chromophobe renal cell carcinoma]].

Latest revision as of 16:31, 13 January 2022

CD117 is common immunostain.

Normal tissue positive

  • Mast cells.[1]
  • Cajal cells.[1]
  • Germ cells.[1]
  • Melanocytes.[1]

Positive

See also

References

  1. 1.0 1.1 1.2 1.3 Miettinen M, Lasota J (September 2005). "KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation". Appl Immunohistochem Mol Morphol 13 (3): 205–20. doi:10.1097/01.pai.0000173054.83414.22. PMID 16082245.
  2. Ulbright TM, Tickoo SK, Berney DM, Srigley JR (August 2014). "Best practices recommendations in the application of immunohistochemistry in testicular tumors: report from the international society of urological pathology consensus conference". Am. J. Surg. Pathol. 38 (8): e50–9. doi:10.1097/PAS.0000000000000233. PMID 24832161.