Difference between revisions of "Prostatic stromal tumour of uncertain malignant potential"

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{{ Infobox diagnosis
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Name      = {{PAGENAME}}
| Image      =  
| Image      = Prostatic stromal tumor of uncertain malignant potential - 1 WBAL.jpg
| Width      =
| Width      =
| Caption    =  
| Caption    = Prostatic stromal tumour of uncertain malignant potential. (WC/George Netto)
| Synonyms  =
| Synonyms  = prostatic stromal proliferation of uncertain malignant potential
| Micro      = increased stromal cellularity, +/-nuclear atypia, +/-benign glands, lack small round blood vessels, no necrosis, no or minimal mitotic activity
| Micro      = increased stromal cellularity, +/-nuclear atypia, +/-benign glands, lack small round blood vessels, no necrosis, no or minimal mitotic activity
| Subtypes  =
| Subtypes  =
| LMDDx      = [[prostatic stromal sarcoma]], stromal nodule in [[benign prostatic hyperplasia]], [[leiomyosarcoma]], [[rhabdomyosarcoma]]
| LMDDx      = [[prostatic stromal sarcoma]], stromal nodule in [[benign prostatic hyperplasia]], [[leiomyosarcoma]], [[rhabdomyosarcoma]], [[sarcomatoid prostate carcinoma]]
| Stains    =
| Stains    =
| IHC        =
| IHC        = CD34 +ve, ER +ve, PR +ve, vimentin +ve, panker -ve{{fact}}
| EM        =
| EM        =
| Molecular  =
| Molecular  =
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*[[Leiomyosarcoma]].
*[[Leiomyosarcoma]].
*[[Rhabdomyosarcoma]].
*[[Rhabdomyosarcoma]].
*[[Sarcomatoid prostate carcinoma]] - often associated with conventional prostate carcinoma & history of radiation.


===Subclassification===
===Subclassification===
May be subclassified as per Gaudin ''et al.'':<ref name=pmid9500215>{{Cite journal  | last1 = Gaudin | first1 = PB. | last2 = Rosai | first2 = J. | last3 = Epstein | first3 = JI. | title = Sarcomas and related proliferative lesions of specialized prostatic stroma: a clinicopathologic study of 22 cases. | journal = Am J Surg Pathol | volume = 22 | issue = 2 | pages = 148-62 | month = Feb | year = 1998 | doi =  | PMID = 9500215 }}
May be subclassified as per Gaudin ''et al.'':<ref name=pmid9500215>{{Cite journal  | last1 = Gaudin | first1 = PB. | last2 = Rosai | first2 = J. | last3 = Epstein | first3 = JI. | title = Sarcomas and related proliferative lesions of specialized prostatic stroma: a clinicopathologic study of 22 cases. | journal = Am J Surg Pathol | volume = 22 | issue = 2 | pages = 148-62 | month = Feb | year = 1998 | doi =  | PMID = 9500215 }}</ref>
</ref>
#Scattered atypical cells with benign glands.  
#Scattered atypical cells with benign glands.  
#Minimal atypical cells.
#Minimal atypical cells.
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===Images===
===Images===
<gallery>
Image: Prostatic stromal tumor of uncertain malignant potential - 1 WBAL.jpg | STUMP - 1 (WC/Netto)
Image: Prostatic stromal tumor of uncertain malignant potential - 2 WBAL.jpg | STUMP - 2 (WC/Netto)
</gallery>
====www====
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-138-11-1542-f01&doi=10.5858%2Farpa.2013-0212-RS STUMP (archivesofpathology.org)].<ref name=pmid25357117>{{Cite journal  | last1 = Murer | first1 = LM. | last2 = Talmon | first2 = GA. | title = Stromal tumor of uncertain malignant potential of the prostate. | journal = Arch Pathol Lab Med | volume = 138 | issue = 11 | pages = 1542-5 | month = Nov | year = 2014 | doi = 10.5858/arpa.2013-0212-RS | PMID = 25357117 }}</ref>
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-138-11-1542-f01&doi=10.5858%2Farpa.2013-0212-RS STUMP (archivesofpathology.org)].<ref name=pmid25357117>{{Cite journal  | last1 = Murer | first1 = LM. | last2 = Talmon | first2 = GA. | title = Stromal tumor of uncertain malignant potential of the prostate. | journal = Arch Pathol Lab Med | volume = 138 | issue = 11 | pages = 1542-5 | month = Nov | year = 2014 | doi = 10.5858/arpa.2013-0212-RS | PMID = 25357117 }}</ref>


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*[[Prostate gland]].
*[[Prostate gland]].
*[[Waffle diagnosis]].
*[[Waffle diagnosis]].
*[[Smooth muscle tumour of uncertain malignant potential]].


==References==
==References==
48,597

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