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Difference between revisions of "Sebaceous carcinoma"
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→Sebaceous carcinoma versus squamous cell carcinoma
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''' | '''Sebaceous carcinoma''', also known as '''sebaceous cell carcinoma''', is an uncommon [[dermatologic neoplasms|skin tumour]]. | ||
==General== | ==General== | ||
*Malignant. | *Malignant. | ||
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Images: | Images: | ||
*[http://archopht.jamanetwork.com/data/journals/ophth/9858/m_ecs8482f1.png Sebaceous carcinoma - EMA, AE1/AE3, CAM5.2 (jamanetwork.com)].<ref name=pmid10369589>{{Cite journal | last1 = Sinard | first1 = JH. | title = Immunohistochemical distinction of ocular sebaceous carcinoma from basal cell and squamous cell carcinoma. | journal = Arch Ophthalmol | volume = 117 | issue = 6 | pages = 776-83 | month = Jun | year = 1999 | doi = | PMID = 10369589 }}</ref> | *[http://archopht.jamanetwork.com/data/journals/ophth/9858/m_ecs8482f1.png Sebaceous carcinoma - EMA, AE1/AE3, CAM5.2 (jamanetwork.com)].<ref name=pmid10369589>{{Cite journal | last1 = Sinard | first1 = JH. | title = Immunohistochemical distinction of ocular sebaceous carcinoma from basal cell and squamous cell carcinoma. | journal = Arch Ophthalmol | volume = 117 | issue = 6 | pages = 776-83 | month = Jun | year = 1999 | doi = | PMID = 10369589 }}</ref> | ||
===Sebaceous carcinoma versus squamous cell carcinoma=== | |||
*CK7 +ve. | |||
**Useful if positive: 24 of 27 sebaceous carcinomas +ve; only 2 of 22 squamous cell carcinomas +ve.<ref name=pmid26485238>{{cite journal |authors=Plaza JA, Mackinnon A, Carrillo L, Prieto VG, Sangueza M, Suster S |title=Role of immunohistochemistry in the diagnosis of sebaceous carcinoma: a clinicopathologic and immunohistochemical study |journal=Am J Dermatopathol |volume=37 |issue=11 |pages=809–21 |date=November 2015 |pmid=26485238 |doi=10.1097/DAD.0000000000000255 |url=}}</ref> | |||
*Ber-EP4 -ve/+ve. | |||
**Useful if positive: 7 of 27 sebaceous carcinomas +ve; 0 of 22 squamous cell carcinomas +ve.<ref name=pmid26485238/> | |||
*EMA +ve. | |||
**Useful if negative: 27 of 27 sebaceous carcinoma +ve; 16 of 22 squamous cell carcinoma +ve.<ref name=pmid26485238/> | |||
==Sign out== | ==Sign out== | ||