Hepatic sarcoidosis: Difference between revisions

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DDx:
DDx:
*[[Drug induced liver disease]].
*[[Drug induced liver disease]].
*[[Primary biliary cirrhosis]].
*[[Primary biliary cholangitis]].
*Infection.
*Infection.
**[[Tuberculosis]].
**[[Tuberculosis]].
**[[Histoplasmosis]].
**[[Histoplasmosis]].
{|
[[File:1 sarcoid 1 680x512px.tif| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
[[File:2 sarcoid 1 680x512px.tif| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
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[[File:3 sarcoid 1 680x512px.tif| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
[[File:4 sarcoid 1 680x512px.tif| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
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[[File:5 sarcoid 1 680x512px.tif| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
[[File:6 sarcoid 1 680x512px.tif| Hepatic sarcoidosis in a patient with previously known sarcoidosis.]]
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Hepatic sarcoidosis in a patient with previously known sarcoidosis. At low power markedly distorted parenchyma is highlighted by seeing the minor component of unaffected cores [parallel to double headed arrowsD] (Row 1 Left 20X). All but the lower left part is affected by a large granuloma strewing Touton body giant cells [arrows] (Row 1 Right 100X). PAS without diastase shows granulomas separated by a small column of hepatocytes (Row 2 Left 200X). Trichrome here shows the extensive fibrosis associated with the granulomatous inflammation in this case(Row 2 Right 200X). Trichrome here demonstrates a utility in picking up giant cells [arrows], whose cytoplasm often stains differently than the surrounding fibrosis (Row 3 Left 200X).  As shown by this trichrome stained image, most triads showed fibrosis; none showed involvement by granuloma or increased chronic stromal inflammation  (Row 3 Right 200X).


==See also==
==See also==