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(→Epidermoid cyst of the testis: create) |
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*Tunica albuginea - fibrous layer. | *Tunica albuginea - fibrous layer. | ||
*Tunica vaginalis - thin mesothelial layer. | *Tunica vaginalis - thin mesothelial layer. | ||
**This layer is important in the [[cancer staging|staging]] of testicular tumours. | |||
===Microscopic=== | ===Microscopic=== | ||
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Image:Seminiferous_tubule_and_sperm_low_mag.jpg | Seminiferous tubule and sperm - low mag. (WC/Nephron) | Image:Seminiferous_tubule_and_sperm_low_mag.jpg | Seminiferous tubule and sperm - low mag. (WC/Nephron) | ||
Image:Seminiferous_tubule_and_sperm.jpg | Seminiferous tubule and sperm - high mag. (WC/Nephron) | Image:Seminiferous_tubule_and_sperm.jpg | Seminiferous tubule and sperm - high mag. (WC/Nephron) | ||
Image:Intratubular_germ_cell_neoplasia_-_2_-_very_high_mag.jpg | Benign seminiferous tubules and ITGCN. (WC/Nephron) | Image:Intratubular_germ_cell_neoplasia_-_2_-_very_high_mag.jpg | Benign seminiferous tubules and GCNIS (ITGCN). (WC/Nephron) | ||
</gallery> | </gallery> | ||
====Interstitial==== | ====Interstitial==== | ||
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! Image | ! Image | ||
|- | |- | ||
| [[ | | [[Germ cell neoplasia in situ]] (GCNIS) | ||
| nests of small fried egg cells | | nests of small fried egg cells | ||
| large central nucleus, clear <br>cytoplasm, round ''or'' polygonal nuclear membrane, [[nucleoli]]<ref name=Ref_GUP538>{{Ref GUP|538}}</ref> | | large central nucleus, clear <br>cytoplasm, round ''or'' polygonal nuclear membrane, [[nucleoli]]<ref name=Ref_GUP538>{{Ref GUP|538}}</ref> | ||
| CD117 | | CD117 | ||
| appearance similar to seminoma | | appearance similar to seminoma | ||
| [[Image:Intratubular_germ_cell_neoplasia_high_mag_cropped.jpg|thumb|center|150px| | | [[Image:Intratubular_germ_cell_neoplasia_high_mag_cropped.jpg|thumb|center|150px|GCNIS (WC)]] | ||
|- | |- | ||
| [[Seminoma]] | | [[Seminoma]] | ||
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| [[Image:Teratoma_2_low_mag.jpg|thumb|center|150px|Teratoma (WC)]] | | [[Image:Teratoma_2_low_mag.jpg|thumb|center|150px|Teratoma (WC)]] | ||
|- | |- | ||
| [[Spermatocytic | | [[Spermatocytic tumour]] (previously ''spermatocytic seminoma'') | ||
| population of 3 cells | | population of 3 cells | ||
| pop.: (1) small cell with high [[NC ratio]] (mature lymphocyte-like), (2) medium with nucleoli, (3) large cells with filamentous chromatin - few present | | pop.: (1) small cell with high [[NC ratio]] (mature lymphocyte-like), (2) medium with nucleoli, (3) large cells with filamentous chromatin - few present | ||
| ? | | ? | ||
| does not arise from | | does not arise from GCNIS, no lymphocytic infiltrate (like in seminoma) | ||
| [[Image:Spermatocytic_seminoma_high_mag.jpg|thumb|center|150px|Spermatocytic | | [[Image:Spermatocytic_seminoma_high_mag.jpg|thumb|center|150px|Spermatocytic tumour (WC)]] | ||
|- | |- | ||
| [[Mixed germ cell tumour]] | | [[Mixed germ cell tumour]] | ||
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==Hydrocele testis== | ==Hydrocele testis== | ||
*[[AKA]] ''hydrocele''. | *[[AKA]] ''hydrocele''. | ||
{{Main|Hydrocele testis}} | |||
==Idiopathic granulomatous orchitis== | ==Idiopathic granulomatous orchitis== | ||
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DDx: | DDx: | ||
*[[ | *[[GCNIS]] (ITGCN). | ||
*[[Seminoma]]. | *[[Seminoma]]. | ||
*Tertiary [[syphilis]] - classically, plasma cell rich.<ref name=pmid22343746>{{Cite journal | last1 = Sekita | first1 = N. | last2 = Nishikawa | first2 = R. | last3 = Fujimura | first3 = M. | last4 = Sugano | first4 = I. | last5 = Mikami | first5 = K. | title = [Syphilitic orchitis: a case report]. | journal = Hinyokika Kiyo | volume = 58 | issue = 1 | pages = 53-5 | month = Jan | year = 2012 | doi = | PMID = 22343746 }}</ref> | *Tertiary [[syphilis]] - classically, plasma cell rich.<ref name=pmid22343746>{{Cite journal | last1 = Sekita | first1 = N. | last2 = Nishikawa | first2 = R. | last3 = Fujimura | first3 = M. | last4 = Sugano | first4 = I. | last5 = Mikami | first5 = K. | title = [Syphilitic orchitis: a case report]. | journal = Hinyokika Kiyo | volume = 58 | issue = 1 | pages = 53-5 | month = Jan | year = 2012 | doi = | PMID = 22343746 }}</ref> | ||
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*[[Lymphoma]].<ref name=pmid21458170/> | *[[Lymphoma]].<ref name=pmid21458170/> | ||
*[[Malakoplakia]].<ref name=pmid21458170/> | *[[Malakoplakia]].<ref name=pmid21458170/> | ||
*BCG-associated orchitis.<ref name=pmid23856256>{{Cite journal | last1 = Parker | first1 = SG. | last2 = Kommu | first2 = SS. | title = Post-intravesical BCG epididymo-orchitis: Case report and a review of the literature. | journal = Int J Surg Case Rep | volume = 4 | issue = 9 | pages = 768-70 | month = | year = 2013 | doi = 10.1016/j.ijscr.2013.05.017 | PMID = 23856256 }}</ref><ref name=pmid12841318>{{Cite journal | last1 = Bulbul | first1 = MA. | last2 = Hijaz | first2 = A. | last3 = Beaini | first3 = M. | last4 = Araj | first4 = GF. | last5 = Tawil | first5 = A. | title = Tuberculous epididymo-orchitis following intravesical BCG for superficial bladder cancer. | journal = J Med Liban | volume = 50 | issue = 1-2 | pages = 67-9 | month = | year = | doi = | PMID = 12841318 }}</ref> | |||
===Stains=== | ===Stains=== | ||
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==Adenomatous hyperplasia of the rete testis== | ==Adenomatous hyperplasia of the rete testis== | ||
{{Main|Adenomatous hyperplasia of the rete testis}} | {{Main|Adenomatous hyperplasia of the rete testis}} | ||
==Epidermoid cyst of the testis== | |||
{{Main|Epidermoid cyst of the testis}} | |||
==Testicular trauma== | |||
===General=== | |||
*May lead to orchitectomy. | |||
===Gross=== | |||
*Hemorrhagic. | |||
===Microscopic=== | |||
Features: | |||
*Necrotic seminiferous tubules. | |||
*Intratubular blood in keeping with hemorrhage. | |||
Note: | |||
*Normal spermatogenesis in background - if viable tissue present. | |||
===Sign out=== | |||
<pre> | |||
Right Testicle Tissue, Debridement: | |||
- Hemorrhagic testicular tissue and necrotic seminiferous tubules. | |||
- Small amount of viable seminiferous tubules with spermatogenesis. | |||
- NEGATIVE for germ cell neoplasia in situ. | |||
- NEGATIVE for malignancy. | |||
Comment: | |||
The clinical history of trauma is noted. | |||
</pre> | |||
=Premalignant= | =Premalignant= | ||
== | ==Germ cell neoplasia in situ== | ||
* | *Previously ''intratubular germ cell neoplasia'' (abbreviated ''ITGCN''). | ||
{{Main| | {{Main|Germ cell neoplasia in situ}} | ||
=Germ cell tumours= | =Germ cell tumours= | ||
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{{Main|Seminoma}} | {{Main|Seminoma}} | ||
==Spermatocytic | ==Spermatocytic tumour== | ||
{{Main|Spermatocytic | *Previously ''spermatocytic seminoma''. | ||
{{Main|Spermatocytic tumour}} | |||
==Yolk sac tumour== | ==Yolk sac tumour== | ||
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:Abbreviated ''TART''. | :Abbreviated ''TART''. | ||
{{Main|Testicular adrenal rest tumour}} | {{Main|Testicular adrenal rest tumour}} | ||
==Fibrous pseudotumour of the paratesticular region== | |||
{{Main|Fibrous pseudotumour of the paratesticular region}} | |||
==Testicular metastasis== | |||
{{Main|Testicular metastasis}} | |||
=See also= | =See also= | ||
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*[[Vas deferens]]. | *[[Vas deferens]]. | ||
*[[Spermatic cord]]. | *[[Spermatic cord]]. | ||
*[[Paratesticular region]]. | |||
=References= | =References= |
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