Difference between revisions of "Keratinous debris"

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'''Keratinous debris''' can be seen in a number of contexts. It is a nonspecific finding in [[dermatopathology]] that should ''not'' be over interpreted.
'''Keratinous debris''' can be seen in a number of contexts. It is a nonspecific finding in [[dermatopathology]] that should ''not'' be over interpreted.
''Keratin flakes'' redirects here.


==General==
==General==
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COMMENT:
COMMENT:
Underlying tissue cannot be evaluated. Clinical correlation is required.
The underlying tissue cannot be evaluated. Clinical correlation is required.
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===Alternate===
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Skin Lesion, Left Forehead, Biopsy:
- Keratinous material with a small amount of epidermis without
  significant atypia, not further diagnostic, see comment.
 
Comment:
The tissue received is very superficial and precludes further diagnostic classification.
 
The dermal-epidermal junction is not seen in the planes of section. The differential diagnosis includes (but is not limited to) hypertrophic actinic keratosis and well-differentiated squamous cell carcinoma.  Complete excision of the lesion is recommended.
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Latest revision as of 14:00, 18 May 2021

Keratinous debris can be seen in a number of contexts. It is a nonspecific finding in dermatopathology that should not be over interpreted.

Keratin flakes redirects here.

General

  • Seen when the clinican cuts of the superficial aspect of a lesion.

Microscopic

Features:

  • Keratinous material - key features.
  • No significant quantity of epidermis.
  • No dermis.

DDx:

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SKIN LESION, LEFT POSTERIOR THIGH, SHAVE BIOPSY:
- KERATINOUS DEBRIS, FRAGMENTS.

COMMENT:
The underlying tissue cannot be evaluated. Clinical correlation is required.

Alternate

Skin Lesion, Left Forehead, Biopsy:
	- Keratinous material with a small amount of epidermis without 
	  significant atypia, not further diagnostic, see comment.

Comment:
The tissue received is very superficial and precludes further diagnostic classification.

The dermal-epidermal junction is not seen in the planes of section. The differential diagnosis includes (but is not limited to) hypertrophic actinic keratosis and well-differentiated squamous cell carcinoma.  Complete excision of the lesion is recommended.

See also