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Difference between revisions of "Ulcerative colitis"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Ulcerative colitis (2) active.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = Active colitis in a case of ulcerative colitis. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = | | Micro = active changes ([[cryptitis]], [[crypt abscesses]], erosions), chronic changes (architectural distortion, basal plasmacytosis, foveolar metaplasia, Paneth cell metaplasia), lack of [[granulomas]], mucin depletion (common) | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = [[Crohn's disease]], [[infectious colitis]], [[ischemic colitis]], [[diversion colitis]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = | ||
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| Grossing = | | Grossing = | ||
| Site = [[colon]] | | Site = [[colon]] | ||
| Assdx = | | Assdx = [[primary sclerosing cholangitis]], [[toxic megacolon]] | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = | | Clinicalhx = +/-FHx of IBD | ||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = +/-diarrhea +/-blood per rectum | ||
| Prevalence = | | Prevalence = uncommon | ||
| Bloodwork = | | Bloodwork = | ||
| Rads = | | Rads = | ||
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| Prognosis = | | Prognosis = | ||
| Other = | | Other = | ||
| ClinDDx = | | ClinDDx = other types colitis ([[infectious colitis|infectious]], [[Crohn's disease]], [[ischemic colitis|ischemic]]) | ||
| Tx = | | Tx = medical and/or surgical | ||
}} | }} | ||
'''Ulcerative colitis''', abbreviated '''UC''', is a type of [[inflammatory bowel disease]]. | '''Ulcerative colitis''', abbreviated '''UC''', is a type of [[inflammatory bowel disease]]. | ||
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***Basal plasmacytosis. | ***Basal plasmacytosis. | ||
***Foveolar metaplasia. | ***Foveolar metaplasia. | ||
***Paneth cell metaplasia (distal). | ***[[Paneth cell metaplasia]] (distal). | ||
**Lack of [[granulomas]]. | **Lack of [[granulomas]]. | ||
*Mucin depletion - common in UC.<ref name=pmid2318990>{{Cite journal | last1 = McCormick | first1 = DA. | last2 = Horton | first2 = LW. | last3 = Mee | first3 = AS. | title = Mucin depletion in inflammatory bowel disease. | journal = J Clin Pathol | volume = 43 | issue = 2 | pages = 143-6 | month = Feb | year = 1990 | doi = | PMID = 2318990 }}</ref> | *Mucin depletion - common in UC.<ref name=pmid2318990>{{Cite journal | last1 = McCormick | first1 = DA. | last2 = Horton | first2 = LW. | last3 = Mee | first3 = AS. | title = Mucin depletion in inflammatory bowel disease. | journal = J Clin Pathol | volume = 43 | issue = 2 | pages = 143-6 | month = Feb | year = 1990 | doi = | PMID = 2318990 }}</ref> | ||
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*[[Ischemic colitis]]. | *[[Ischemic colitis]]. | ||
*[[Diversion colitis]]. | *[[Diversion colitis]]. | ||
*[[Diverticular disease-associated colitis]]<ref name=pmid12406450>{{Cite journal | last1 = Ludeman | first1 = L. | last2 = Warren | first2 = BF. | last3 = Shepherd | first3 = NA. | title = The pathology of diverticular disease. | journal = Best Pract Res Clin Gastroenterol | volume = 16 | issue = 4 | pages = 543-62 | month = Aug | year = 2002 | doi = | PMID = 12406450 }}</ref> restricted to areas with [[diverticular disease]]. | |||
===Images=== | |||
<gallery> | |||
Image: Ulcerative colitis (2) endoscopic biopsy.jpg | UC. (WC/KGH) | |||
Image: Ulcerative colitis (2) active.jpg | UC. (WC/KGH) | |||
Image: Ulcerative_colitis_(1)_active.jpg | UC. (WC/KGH) | |||
</gallery> | |||
==Sign out== | ==Sign out== | ||
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*[[Inflammatory bowel disease]]. | *[[Inflammatory bowel disease]]. | ||
*[[Crohn's disease]]. | *[[Crohn's disease]]. | ||
*[[Invisible colonic dysplasia]]. | |||
==References== | ==References== | ||